직접 또는 간접적인 봉독에 의한 안구 독성 2예에 대한 비교 및 고찰

• 영문명: A Report of Two Case of Ocular Toxicity Resulting from Direct or Indirect Bee Venom
• 발행기관: 대한안과학회
• 저자명: 이찬호(Chan Ho Lee) 이창환(Chang Hwan Lee) 장무환(Moo Hwan Chang) 서영승(Young Seung Seo)
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume60,number4, 399~405쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2019.04.30

영문 초록

Purpose: To report a patient stung by a bee, who was diagnosed with sterile endopthalmitis and another patient diagnosed with optic neuritis, with decreasing visual acuity, after refined bee venom injection around the orbital tissue. Case summary: A 82-year-old female visited our hospital for decreased visual acuity in the right eye and ocular pain due to a bee sting. The bee sting penetrated the sclera into the vitreous. In the anterior segment, severe cornea edema and anterior chamber cells were seen. Using ultrasonography, inflammation was seen around the intravitreal area. After 3 months, intravitreal inflammation regressed but the patient’s visual acuity was light perception negative, and corneal opacity, neovascularization, and phthisis bulbi were detected. A 55-year-old male visited our hospital for ocular pain in the right eye and decreasing visual acuity after refined bee venom injection around the orbital tissue. The best-corrected visual acuity in the right eye was 15/100, there was moderate injection on the conjunctiva. A relative afferent pupillary defect, abnormal color vision test results, and a defect in the visual field test were observed. There was no pain during external ocular movement, and other general blood tests, and a brain MRI were normal. Based on these symptoms, methylprednisolone megatherapy was started for treatment of optic neuritis. After treatment, visual acuity of the right eye was 9/10 and all other clinical optic neuritis symptoms regressed. Conclusions: Based on these two cases, ocular toxicity from bee venom could result from both direct and indirect courses. Treatment using refined bee venom might be harmful, and caution is recommended in its use. J Korean Ophthalmol Soc 2019;60(4):399-405

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키워드

Bee venom Inflammation Optic neuritis