Diabetic Retinopathy and Peripapillary Retinal Thickness

• 발행기관: 대한안과학회
• 저자명: Hee Yoon Cho Dong Hoon Lee Song Ee Chung Se Woong Kang
• 간행물 정보: 『The Korean Journal of Ophthalmology』Vol.24 No.1, 16~22쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2010.02.28

영문 초록

Purpose: To assess the diagnostic efficacy of macular and peripapillary retinal thickness measurements for the staging of diabetic retinopathy (DR) and the prediction of disease progression. Methods: In this prospective study, 149 diabetic patients (149 eyes) and 50 non-diabetic control subjects were included. Baseline optical coherence tomography was employed to measure retinal thickness in the macula (horizontal, vertical, and central) and the peripapillary zone (superior, inferior, nasal, and concentric to the optic disc). Seven baseline parameters were correlated with the DR stages identified by fluorescein angiography. Baseline retinal thickness was compared between groups of patients requiring panretinal photocoagulation(PRP) within 6 months (PRP group) and patients not requiring PRP (No-PRP group). Results: Macular and peripapillary retinal thicknesses in diabetic subjects were significantly greater than that in normal controls (p<0.05). All retinal thickness parameters, and particularly peripapillary circular scans, tended to increase with increasing DR severity (p<0.05). The baseline thicknesses of the peripapillary circular scans were greater in the PRP group than in the no-PRP group (p<0.05). Conclusions: Peripapillary retinal thickness may prove to be a useful criterion for DR severity and may also serve as an indicator of disease progression.

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키워드

Diabetic retinopathy Laser photocoagulation Retina Mass screening