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학술논문

Human Papilloma Virus in Retinoblastoma Tissues from Korean Patients

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영문명
발행기관
대한안과학회
저자명
Na-Kyung Ryoo Ji-Eun Kim Ho-Kyung Choung Namju Kim Min-Jeong Lee Sang-In Khwarg
간행물 정보
『The Korean Journal of Ophthalmology』Vol.27 No.5, 368~371쪽, 전체 4쪽
주제분류
의약학 > 기타의약학
파일형태
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발행일자
2013.10.30
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Purpose: Recent reports suggest the association of human papilloma virus (HPV) with retinoblastoma. This study was performed to elucidate whether HPV infection is related to retinoblastoma among Koreans. Methods: A total of 54 cases diagnosed with retinoblastoma were enrolled from Seoul National University Children’s Hospital and Seoul Metropolitan Government- Seoul National University Boramae Medical Center. Presence of human papilloma viral DNA was detected by in situ hybridization in formalin-fixed paraffin-embedded retinoblastoma tissues using both probes against high- and low risk HPV types. Results: The mean age at diagnosis was 22.0 months (range, 1.1 to 98.0 months), and the mean age at enucleation was 27.8 months (range, 1.5 to 112.7 months) among the 54 patients with retinoblastoma. HPV was not detected in any of the retinoblastoma samples using either high risk or low risk HPV probes. Conclusions: Our study, being the first study in the Korean population, proposes that HPV infection may have no causal relationship with retinoblastoma in Koreans.

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APA

Na-Kyung Ryoo,Ji-Eun Kim,Ho-Kyung Choung,Namju Kim,Min-Jeong Lee,Sang-In Khwarg. (2013).Human Papilloma Virus in Retinoblastoma Tissues from Korean Patients. The Korean Journal of Ophthalmology, 27 (5), 368-371

MLA

Na-Kyung Ryoo,Ji-Eun Kim,Ho-Kyung Choung,Namju Kim,Min-Jeong Lee,Sang-In Khwarg. "Human Papilloma Virus in Retinoblastoma Tissues from Korean Patients." The Korean Journal of Ophthalmology, 27.5(2013): 368-371

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