Oral lesions associated with human immunodeficiency virus in 75 adult patients: a clinical study

• 발행기관: 대한구강악안면외과학회
• 저자명: Antoine Berberi Georges Aoun
• 간행물 정보: 『대한구강악안면외과학회지』대한구강악안면외과학회지 제43권 제6호, 388~394쪽, 전체 7쪽
• 주제분류: 의약학 > 내과학
• 파일형태: PDF
• 발행일자: 2017.12.30

영문 초록

Objectives: The objective of this study was to investigate the presence of oral lesions in human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) patients in a descriptive cross-sectional study, and to establish their presence according to levels of CD4+ cells (including the CD4+/CD8+ cell ratio). Materials and Methods: A total of 75 patients infected with HIV were included. Oral lesions were observed and classified using World Health Organization classification guidelines. Potential correlations between the presence and severity of oral lesions and CD4+ cells, including the CD4+/CD8+cell ratio, were studied. Results: The most frequent oral lesion detected was oral pseudomembranous candidiasis (80.0%), followed by periodontal disease (40.0%), herpetic lesions (16.0%), hairy leukoplakia (16.0%), gingivitis (20.0%), oral ulceration (12.0%), Kaposi’s sarcoma (8.0%), and non-Hodgkin’s lymphoma (4.0%). The CD4+ count was <200 cells/mm3 in 45 cases (60.0%), between 200-500 cells/㎣ in 18 cases (24.0%), and >500 cells/㎣ in 12 cases (16.0%). The mean CD4+ count was 182.18 cells/㎣. The mean ratio of CD4+/CD8+ cells was 0.26. All patients showed at least one oral manifestation. Conclusion: There was no correlation between the CD4+/CD8+ cell ratio and the presence of oral lesions. The severity of the lesions was more pronounced when the CD4+ cell count was less than 200 cells/㎣.

목차

Abstract

Ⅰ. Introduction

Ⅱ. Materials and Methods

Ⅲ. Results

Ⅳ. Discussion

Ⅴ. Conclusion

Conflict of Interest

ORCID

References

키워드

Acquired immunodeficiency syndrome CD4+ HIV Oral lesions