Clinical Experience of Isolated Metachronous Adrenal Gland Metastases from Solid Primary Carcinomas

• 발행기관: 대한내분비외과학회
• 저자명: Min Jae Cho Jae Won Cho Yu-mi Lee Tae-Yon Sung Jong Ho Yoon Ki-Wook Chung Suck Joon Hong
• 간행물 정보: 『The Koreran journal of Endocrine Surgery』17권2호, 73~79쪽, 전체 7쪽
• 주제분류: 의약학 > 일반외과학
• 파일형태: PDF
• 발행일자: 2017.06.30

영문 초록

Purpose: Owing to the development of improved techniques, the use of adrenal gland surgery for the treatment of metachronous metastatic adrenal tumors originating from primary carcinomas has increased. Here, we have analyzed the postoperative outcomes of patients who received surgical treatment for isolated metastatic adrenal gland originated from solid primary carcinomas. Methods: Patients who underwent metastatic adrenalectomy after treatment of the primary carcinoma at the Asan Medical Center from 2000 to 2010 were included. Clinicopathological parameters were analyzed to determine the prognostic outcomes. Results: Our study cohort consisted of 21 patients with hepatocellular carcinoma (n=10), lung carcinoma (n=8), and colorectal carcinoma (n=3). The mean age was 54.6 years old. The mean overall survival (OS) duration was 78.5 months. Disease-specific recurrence-free survival (RFS) after metastatic adrenalectomy was significantly longer when the interval between primary carcinoma treatment and metachronous metastasis to the adrenal glands was ≥16 months (P=0.043). There was no significant difference in disease-specific RFS between patients who underwent open adrenalectomy (OA) vs. laparoscopic adrenalectomy (LA) (P=0.063). Conclusion: Surgical treatment should be recommended for isolated metachronous adrenal gland metastases when the interval between primary carcinoma treatment and metastasis is ≥16 months to achieve better disease-specific RFS. LA was not inferior to OA.

목차

INTRODUCTION

METHODS

RESULTS

DISCUSSION

CONCLUSION

REFERENCES

키워드

Adrenal glands Neoplasm metastasis Neoplasms, second primary Adrenalectomy Survival