자동산화 Methyl Linoleate가 Mouse혈청의 효소활성에 미치는 영향 (급성 독성)

• 영문명: The Effect of Autoxidized Methyl Linoleate on the Serum Enzyme Activity in the Mouse (Acute Toxicity)
• 발행기관: 한국응용과학기술학회 (구.한국유화학회)
• 저자명: Tai Hong Paik(白台鴻) Nak Seung Chung(鄭樂昇)
• 간행물 정보: 『한국응용과학기술학회지』한국유화학회지 제1권 제1호, 23~31쪽, 전체 9쪽
• 주제분류: 공학 > 화학공학
• 파일형태: PDF
• 발행일자: 1984.11.30

영문 초록

In order to investigate the acute toxicity of autoxidized methyl linoleate(AOML) on the activity of serum enzymes in the mouse, we administered once 0.45ml of AOML to ICR strain mouse by using stomach tube. The following results were obtained: The total lactic dehydrogenase(LDH) activities in the serum of AOML group were generally increased than those of normal group. According to electrophoresis, the activities of LDH, were increased while those of LDH, were decreased. The activities of glutamic oxaloacetic transaminase(GOT), glutamic-pyruvic transaminase(GPT) and α-amylase in the serum of AOML group were increased more than those of normal group. The activities of alkaline phosphatase in the serum of AOML group were increased but those of isozyme were not confirmed in the normal and AOML group. In the serum protein of AOML group, albumin was increased, on the other hand γ-globulin was decreased. At the peripheral blood slide smear, lymphocytes were significantly decreased but neutrophils were increased and the morphological change of erythrocytes was observed. From these results we conclude that the AOML fed to mouse influences on the activity of various serum enzymes and blood cells in the mouse.

목차

Abstract

I. 서론

II. 실험 방법

III. 결과 및 고찰

요지

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