가교제를 이용한 Sulfanilamide 중합체의 합성과 항균특성

• 영문명: Characterization of Antibacterial activity and Synthesis of Sulfanilamide Polymer using Crosslinking Agent
• 발행기관: 한국응용과학기술학회 (구.한국유화학회)
• 저자명: 김종완(Jong Woan Kim) 윤철훈(Chul Hun Yoon) 황성규(Sung Kwy Hwang) 공승대(Seung Dae Kong) 이한섭(Han Seab Lee)
• 간행물 정보: 『한국응용과학기술학회지』한국유화학회지 제17권 제1호, 37~42쪽, 전체 6쪽
• 주제분류: 공학 > 화학공학
• 파일형태: PDF
• 발행일자: 2000.03.30

영문 초록

Drug delivery system(DDS) have been actively studied for the past twenty years. Dual action agents are unique chemical entities comprised of two different types of antibacterial compounds covalently linked together in a single molecule in such a way that both components are able to exert their bactericidal properties. In spite of the advent of the antibacterial agent the sulfa agents are the most widely used antibacterial agent today. In this study, new antibacterials derivative was synthesized using glutaraldehyde such as crosslinking agent for the purpose of dual-action as DDS study. Antibacterial activity of these new synthetic derivative between their structures and activities were examined by disc diffusion method. As a result, new synthetic derivative exhibited the broad antibacterial activities against Gram(＋) and Gram(－) bacilli. Especially, the antibacterial effect of new synthetic derivative against Gram negative(Esherichia. coli) was much stronger than that against Gram positive.

목차

Abstract

Ⅰ. 서론

Ⅱ. 재료 및 방법

Ⅲ. 결과 및 고찰

Ⅳ. 결론

참고문헌