하수오 추출물의 혈당강하작용

• 영문명: Antidiabetic Effect of Ha-Su-O(polygoni radix)
• 발행기관: 한국응용과학기술학회 (구.한국유화학회)
• 저자명: 김옥경(Ok Kyung Kim)
• 간행물 정보: 『한국응용과학기술학회지』한국유화학회지 제25권 제3호, 347~354쪽, 전체 8쪽
• 주제분류: 공학 > 화학공학
• 파일형태: PDF
• 발행일자: 2008.09.30

영문 초록

This study was done to investigate the antidiabetic effect of polygoni radix in Streptozotocin(STZ)-induced diabetic rats. Diabetes was induced by intravenous injection of STZ at a dose of 45mg/kg dissolved in citrate buffer. The ethanol extract of polygoni radix was orally administrated once a day for 7 days. The content of serum glucose, triglyceride(TG), total cholesterol were significantly decreased in polygoni radix treated STZ-sample group compared to the those of STZ-control group. The content of hepatic glycogen and activities of glucose-6-phosphate dehydrogenase(Glucose-6-PDH), glucokinase were significantly increased, but activity of glucose-6-phoshatase was decreased in polygoni radix treated STZ-sample group compared to the those of STZ-control group. These results indicated that ethanol extract of polygoni radix would have antidiabetic effect in STZ-induced diabetic rats.

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키워드

streptozotocin antidiabetic effects polygoni radix