C57BL/6 마우스에서 천연 식물성추출물(아벨모)의 발모효능 및 작용 메카니즘

• 영문명: Effect of natural plant extract (Abelmo) on action mechanism and hair growth activities in C57BL/6 mice
• 발행기관: 한국응용과학기술학회 (구.한국유화학회)
• 저자명: 박상오Sang-Oh Park 박병성Byung-Sung Park 노가영Ga-Yeong Noh
• 간행물 정보: 『한국응용과학기술학회지』한국유화학회지 제31권 제4호, 653~662쪽, 전체 10쪽
• 주제분류: 공학 > 화학공학
• 파일형태: PDF
• 발행일자: 2014.12.31

영문 초록

This study was determined the hair growth effect and mode of action of a complex extract (abelmo), extracted from various natural plants including Acorus calamus var. angustatus. 30 six-week old C57BL/6 mice were randomly assigned into three treatment groups with ten mice per treatment group repeatedly. The treatment group is a control group, and was classified into saline-applied, minoxidil 5%-applied, and abelmo-applied groups. Hair growth started from the abelmo-applied and minoxidil 5% -applied groups on the 9th day, compared to the saline-applied group. Hair growth rate was 17.06% and 19.15% in those two groups, respectively, and the abelmo-applied group s hair growth rate was higher. The density, length and thickness of hair were significantly higher in the order of abelmo-applied group, minoxidil 5%-applied group and saline-applied group on the 9th day, and hair root was strongly maintained in the abelmo-applied group. The density, length and thickness of hair in the abelmo-applied group were significantly higher by 599.8, 122.2 and 181.8% on the 9th day compared to the saline-applied group, and 166.7, 171.4 and 200.2% on the 12th day, and 136.6, 216.9 and 180.7%, respectively on the 15th day. As for hair follicle and the length of hair shaft from the dosal skin histopathology manifestation, the abelmo-applied group was more excellent than the saline-applied group and minoxidil 5%-applied group. This result actually confirmed the fact that abelmo promotes hair growth and strongly maintains hair root simultaneously.

목차

1. 서 론

2. 실 험

3. 결과 및 고찰

4. 결 론

References

키워드

Abelmo hair growth rate density length thickness skin histopathology.