有機憐中毒에 대한 甘豆抽出液의 防禦效果

• 영문명: Preventive Efficacy of Kam Doo Extract Against Dichlovos Intoxication in Mouse
• 발행기관: 한국환경보건학회
• 저자명: 金學燁(Hak Yeop Kim) 林國煥(Kook Hwan Rhim)
• 간행물 정보: 『1. 한국환경보건학회지』제15권 제2호, 75~83쪽, 전체 9쪽
• 주제분류: 공학 > 환경공학
• 파일형태: PDF
• 발행일자: 1989.11.30

영문 초록

To evaluate the effect of Kam Doo-extract (KDE) on organophosphorous (OP)intoxication in mouse, this research was conducted. KDE prescribed with the equal weights of both Padix Glycyrrizae and Simen Glycine was extracted in water at 100℃ for 2hr, and concentrated in a vacuum evaporator. Animmal used in this research was ICR-strained male mice (bodyweight: 20 ~ 25g), and induction material for OP intoxication was DDVP(Dichlovos). Toxicity parameters used to evaluate KDE-preventive effect on DDVP were cholinesterase activity, and protection index of KDE against LDso values of DDVP. As the results, KDE prevented the inhibition of cholinesteranse activity due to DDVP-treatment, and inhanced the protecion index. Consequently our experimental data show the KDE will be useful as an preventive agent in respect that KDE is safe and effective against OP intoxication in mouse.

목차

Ⅰ. 서 론

Ⅱ. 실험재료 및 방법

Ⅲ. 결 과

Ⅳ. 고 찰

Ⅴ. 결 론