초기 설암에서의 광역학치료

• 영문명: PHOTODYNAMIC THERAPY FOR EARLY TONGUE CANCER
• 발행기관: 대한구강악안면외과학회
• 저자명: 김용각(Yong Kack Kim) 박형국(Hyung Kook Park) 현재훈(Jae Hoon Hyun) 김재환(Jae Hwan Kim) 조병호(Byung Ho Cho)
• 간행물 정보: 『대한구강악안면외과학회지』대한구강악안면외과학회지 제24권 제2호, 222~225쪽, 전체 4쪽
• 주제분류: 의약학 > 내과학
• 파일형태: PDF
• 발행일자: 1998.04.30

영문 초록

The standard methods of treatment in oral and maxillofacial cencer are surgery, radiotherapy and chemotherapy. But all of them can induce significant morbidities, surgery in this area can cause remarkable junctional and esthetic problems. The applications of photodynamic therapy(PDT) has been studying and trying in these days to minimize post-treatment complications. It can almost directly affect tumor cells except surrounding normal tissues, so we are able to reduce post-operative complications. But there can be a couple of complications after PDT, as like skin photosensitivity, so therapists must attend to its use and completely understand their mechanism before doing it. In our clinic, PDT was tried in an early tongue cancer patient using topically applied delta-aminolaevulinic acid (δ-ALA). The 64-year-old man was gargled with 5% δ-ALA 4 hours before irradiation. The previous punched biopsy was reported as well differentiated squamous cell carcinoma(T1N0M0). Light of 635nm wave-length from argon-pumper dye laser was used. Total 150J/cm2 was applied. After 10 days, PDT was applied again in a small suspicious area, 10 days after then, small area was excised and examined histologically. It was revealed as cancer free. Now, the patient was periodically checked up. Conclusively, PDT can be thought to be a acceptable alternative and promising method in treating of early oral and maxillofacial cancer.

목차

Abstract

I. 서론

II. 증례보고

III. 총괄 및 고찰

IV. 결론

참고문헌

키워드

photodynamic therapy (PDT) delta-aminolaevulinic acid (δ-ALA) tongue cancer argon-pumped dye laser