학술논문
백서 대퇴동맥 외막층 제거후 혈관동결시 조직형태학적 변화 및 재생에 관한 연구
이용수 0
- 영문명
- HISTOMORPHOLOGIC CHANGE AND REGENERATION OF THE ADVENTITIA-STRIPPED AND FROZEN RAT FEMORAL ARTERY : HISTOLOGIC , HISTOMORPHOMETERIC , IMMUNOHISTOCHEMICAL AND SCANNING ELECTRON MICROSCOPIC STUDY
- 발행기관
- 대한구강악안면외과학회
- 저자명
- 김태득(Tae Deung Kim) 김경욱(Kyung Wook Kim) 이재훈(Jae Hoon Lee) 김창진(Chang Jin Kim)
- 간행물 정보
- 『대한구강악안면외과학회지』대한구강악안면외과학회지 제25권 제4호, 281~294쪽, 전체 14쪽
- 주제분류
- 의약학 > 내과학
- 파일형태
- 발행일자
- 1999.10.30
4,480원
구매일시로부터 72시간 이내에 다운로드 가능합니다.
이 학술논문 정보는 (주)교보문고와 각 발행기관 사이에 저작물 이용 계약이 체결된 것으로, 교보문고를 통해 제공되고 있습니다.
국문 초록
영문 초록
Vasospasm causes microvascular surgery to fail as a main factor in the loss of transferred flap dye to the diminution of blood flow in reconstruction surgery. Although there has been extensive research to resolve the vasospasm problem, no one has reached an ideal solution to date. However, cryotherapy, which is often used for destruction of tumor lesions, is being presented as a new way of releasing vasospasm. After making a histomorphometric measurement on vasodialation during the course of 1, 3 and 7 days, 2 and 4 weeks, and 5 months periods and observing the change of blood vessel in a histologic, immunohistochemical, and scanning electronic microscopic approach, the results were as follows :
1. Vascular inner diameters of the experimental 1 and 3 days groups were measured 476.3±28.20㎛, 497.15±48.79㎛ repectively showing statistically meaningful vasodilation(P<0.05), which continued by the experiment 4 weeks group. However, in the experimental 5 months group, the vascular inner diameter appeared similar to the control groups. Even though the thickness of smooth muscular layers come out to be thinner in all the experimental groups compared to the control group, it was difficult to find any statistical meaningfulness. In addition, the vascular external diameters of every experimental groups were shown to be longer than the control group.
2. In light microscopic view, severe injury was evident on the smooth muscular layer cell from the experimental 1 day group, started recovering partially from the experimental 7 days group, and was mostly restored in the experimental 4 weeks group and layer of adventitial stripping were nearly recoverd 2 weeks group.
3. The PCNA positive cells of smooth muscular layer were observed from the experimental 7 days group and had a tendency to increase by the experimental 2 weeks group. In the experimental 4 weeks and 5 months group, the number of PCNA possitive cells observed was comparable to the control group.
4. α-SMA level of smooth muscular layer cells, having been significantly lower than the control group in the severly damaged experimental 1 day group. It was seen to be increased in the experimental 7 days group and turned out to show similar α-SMA level in 4 weeks to the control group.
5. In the view of SEM, the endothelial cells were destructed and falling off, and also present the appearance of flattening in the experiment 1 day group. The endothelial layer cells started partially recovering from the 7 days group after the freezing injury. On 4 weeks and 5 months, the endothelial cells were fully coverd the damaged area, also it s appearance is similar to control group.
In conclusion, the vascular freezing after the removal of adventitia caused damages to smooth muscular layer cells, and brought about vasodilation, which continued by the 4th week. The smooth muscular layer cells started partially reviving from the 7rd day after the damage by vascular freezing, and recovered their similar figure to the control group s 4 weeks later. This was considered the result of cells which surround the damaged blood vessel being influxed into the smooth muscular layers. Therefore, this local freezing injury on the blood vessel was thought to be applied clinically to relieve severe vasospasm which cannot be treated by vasodilation drug, a microvascular surgery.
목차
Abstract
Ⅰ. 서론
Ⅱ. 연구재료 및 방법
Ⅲ. 연구결과
Ⅳ. 총괄 및 고찰
Ⅴ. 결론
참고문헌
키워드
해당간행물 수록 논문
- 상악골 수평골절단술 후 비외형 변화에 관한 임상적 연구
- 극심한 술후 출혈 : 증례보고
- 악간고정이 호흡기능에 미치는 영향에 대한 임상적 연구
- 피질골절단술을 이용한 상악협소증환자의 치험례
- 미노싸이클린 연고의 근육 내 투여후 조직 및 혈중 약물농도의 분석
- 악관절 내장증 환자와 정상인의 두부방사선규격사진의 분석비교
- 토끼 하치조신경 전위술 후의 신경 및 신경주변조직 변화 관찰을 위한 예비 실험
- Rapid Prototyping으로 제작한 3D Medical Model의 오차 측정에 관한 연구 - 임상적용 가능성 및 사례
- 발생 치배와 치성 종양에서 Osteonectin발현에 관한 연구
- 악골절 치료후 부정유합에 관한 임상적 연구
- 새 천년의 시작에 즈음하여
- 백서 대퇴동맥 외막층 제거후 혈관동결시 조직형태학적 변화 및 재생에 관한 연구
- 악관절원판의 인위적 전방변위술시행후 악관절구성조직에서 Fibronectin의 분포변화
- 패혈증으로 진행된 치성 감염 : 증례보고
참고문헌
관련논문
의약학 > 내과학분야 BEST
- Zirconia abutment의 활용 Part I
- 임플란트 주위염의 진단과 치료
- Tetracycline & Er-YAG laser 을 이용한 오염된 임플란트 표면의 처치를 통한 임플란트 주위염의 외과적 치료에 대한 증례보고
의약학 > 내과학분야 NEW
- It was ‘up to code’ - but rules predate the age of advanced technology: it was suitable then but not now
- Burning measure for burning mouth syndrome: a systematic review
- Jaws of knowledge: an analysis of temporomandibular joint insights in dental training—a quasi-experiment study
최근 이용한 논문
교보eBook 첫 방문을 환영 합니다!
신규가입 혜택 지급이 완료 되었습니다.
바로 사용 가능한 교보e캐시 1,000원 (유효기간 7일)
지금 바로 교보eBook의 다양한 콘텐츠를 이용해 보세요!