백서 하악골에서 신연골형성술시 신장력과 수축력 복합적용후의 조직반응

• 영문명: TISSUE REACTION FOLLOWING BY COMBINATION OF DISTRACTION AND COMPRESSION FORCE ON DISTRACTION OSTEOGENESIS OF THE MANDIBLE IN THE RAT
• 발행기관: 대한구강악안면외과학회
• 저자명: 김욱규(Uk-Kyu Kim) 신상훈(Sang-Hun Shin) 정인교(In-Kyo Chung) 이광호(Kwang-Ho Lee) 박봉수(Bong-Soo Park)
• 간행물 정보: 『대한구강악안면외과학회지』대한구강악안면외과학회지 제28권 제2호, 103~113쪽, 전체 11쪽
• 주제분류: 의약학 > 내과학
• 파일형태: PDF
• 발행일자: 2002.04.30

영문 초록

Distraction osteogenesis is a biologic process of new bone formation between the surfaces of bone segments that are gradually separated by incremental traction. Distraction osteogenesis is clinically applied as a new treatment modality of mandibular hypoplasia or bony defect area in maxillofacial area by many studies of distraction devices and method. But, disadvantages of distraction osteogenesis shows unfavorably long consolidation period and relapse tendency. Therefore, this experiment was designed to investigate the effectiveness of combined application of distraction and compression force for improving of bone quality and shortening of treatment period during distraction osteogenesis. Twenty-five Sprague-Dawley rats with 300-350gm were used. These were divided into two group as distraction group and combination group. The distraction group was added with conventional method during distraction osteogenesis, but the combination group was applied with compression force in the consolidation period. The rats were sacrificed for gross finding, radiographic and histologic findings at 3, 6 weeks after distraction. The results were as follow: 1. On radiographic finding, all combination of distraction and compression force group appeared more radiopacity than distraction group both at 3 weeks and 6 weeks after distraction group. 2. On histologic finding, the formation of mature lamellar bone were showed increasingly in combined group at 6weeks after distraction group. From this study, we may suggest that compression force application in consolidation period during distraction osteogenesis can be useful method to improve bone quality and to shorten the treatment period. But more experimental and clinical studies is necessitated on ideal application timing and method of compression force application during distraction osteogenesis.

키워드

Distraction Compression Force