골 재생을 위한 생물학적 유도막

• 영문명: BIOLOGIGIC MEMBRANE FOR GUIDED BONE REGENERATION
• 발행기관: 대한구강악안면외과학회
• 저자명: 홍종락(Jong-Rak Hong) 강나라(Nara Kang) 정필훈(Pill-Hoon Choung)
• 간행물 정보: 『대한구강악안면외과학회지』대한구강악안면외과학회지 제30권 제1호, 17~24쪽, 전체 8쪽
• 주제분류: 의약학 > 내과학
• 파일형태: PDF
• 발행일자: 2004.02.28

영문 초록

The purpose of this study was to evaluate the stability and efficacy of biologic membrane made of freeze-dried cartilage as a barrier to facilitate guided bone regeneration in experimental non-healing bone defects in the rat mandible. Nine adult Sprague-Dawley rats(400-500g) were used in experiment. 5.0mm in diameter were created on the mandibular angle area by means of slow-speed trephine drill. In microscopic examination, dynamic immature bone forming at 2 weeks and its calcification at 4 weeks were observed. The membrane made of lyophilized cartilage taken from human costal cartilage seems to be very effective for guided bone regeneration as a biologic membrane and the scaffold for attachment of cells or local drug delivery system of growth factor, which may meet the ideal requirement of a barrier membrane and graft materials

키워드

Freeze-dried cartilage Guided bone regeneration