낭종 수술 전후에 있어서 혈중 Alkaline Phosphatase의 변화에 대한 연구

• 영문명: CHANGES OF SERUM ALKALINE PHOSPHATASE AFTER ENUCLEATION OF CYSTS IN THE JAWS
• 발행기관: 대한구강악안면외과학회
• 저자명: 윤정주(Jung-Ju Eune) 이의석(Eui-Seok Lee) 임재석(Jae-Suk Rim) 장현석(Hyon-Seok Jang) 우현일(Hyon-Il Woo)
• 간행물 정보: 『대한구강악안면외과학회지』대한구강악안면외과학회지 제31권 제5호, 417~421쪽, 전체 5쪽
• 주제분류: 의약학 > 내과학
• 파일형태: PDF
• 발행일자: 2005.10.30

영문 초록

This study was to analyze the changes of levels of alkaline phosphatase before and after enucleation of jaw cysts combined with bone grafting, and to evaluate biochemically the effectiveness of the early detection of bone healing and infection as a prognostic marker. Eighteen patients (13 males, 5 females) with cystic lesions of the jaws were divided into two groups. The bone graft group underwent enucleation and bone graft. The control group underwent only enucleation. Both groups were measured levels of ALP before surgery, and plus-minus 4 weeks postoperatively. The more discriminating results were obtained in the bone graft group. The results were as follows : 1. Levels of ALP after enucleation of jaw cysts were decreased in all patients with and without bone graft. 2. The bone graft group showed more marked decrease in variation of levels of ALP than the control group.(p=0.008) This should be considered as a result of increased osteoblastic activity and new bone formation. 3. Such variation could be used as a prognostic marker for bone healing after cyst operation. In the cost/benefit ratio, measurement of ALP activity could be useful as a convenient procedure in routine clinical practice.

키워드

Alkaline phosphatase Odontogenic cyst Healing