Recombinant human erythropoietin을 이용한 무수혈 구강암절제 및 재건

• 영문명: Oral cancer resection and reconstruction without blood transfusion by using recombinant human erythropoietin
• 발행기관: 대한구강악안면외과학회
• 저자명: 김철환(Chul-Hwan Kim) 이충현(Chung-Hyun Lee)
• 간행물 정보: 『대한구강악안면외과학회지』대한구강악안면외과학회지 제37권 제1호, 9~14쪽, 전체 6쪽
• 주제분류: 의약학 > 내과학
• 파일형태: PDF
• 발행일자: 2011.02.28

영문 초록

Recently, the population of patients who refuse transfusion has increased for both religious and non-religious reasons, even in life threatening emergency situations. Their refusal has highlighted the need to develop nonblood transfusion surgery techniques to decrease the risk from blood transfusions. A 57-year woman with an ulcerative lesion on the gingiva of the right upper molar area visited the department of oral and maxillofacial surgery in Dankook University Dental Hospital. After a preliminary evaluation, the patient was diagnosed with squamous cell carcinoma. As she refused blood transfusion during surgery for religious reasons, surgery was planned using recombinant human erythropoietin (rHuEPO) without a blood transfusion. The patient underwent a partial maxillectomy, supraomohyoid neck dissection, free radial forearm flap and split thickness skin graft under general anesthesia. rHuEPO and iron were used before and after surgery. The hemoglobin/hematocrit (Hb/Hct) level, iron (Fe) and total iron-binding capacity (TIBC) were assessed. The patient recovered completely without any blood transfusions. rHuEPO is a viable alternative for patients with religious objections to receiving blood transfusions.

목차

Ⅰ. 서 론

Ⅱ. 증례보고

Ⅲ. 고 찰

Ⅳ. 결 론

키워드

Recombinant erythropoietin Blood transfusion Mouth neoplasms