구강설에 발생한 편평상피세포암의 특성과 치료효과

• 영문명: The characteristics and treatment results of squamous cell carcinomas of oral tongue
• 발행기관: 대한구강악안면외과학회
• 저자명: 김기호(Ki-Ho Kim) 최은주(Eun-Joo Choi) 김형준(Hyung-Jun Kim) 남 웅(Woong Nam) 차인호(In-Ho Cha)
• 간행물 정보: 『대한구강악안면외과학회지』대한구강악안면외과학회지 제37권 제1호, 15~20쪽, 전체 6쪽
• 주제분류: 의약학 > 내과학
• 파일형태: PDF
• 발행일자: 2011.02.28

영문 초록

Introduction: The characteristics of oral tongue squamous cell carcinomas (SCC) and the treatment results were reviewed to determine the appropriate treatment strategies. Materials and Methods: The medical records of 140 patients diagnosed and treated for oral tongue SCC at Yonsei University Health System from January 1995 to December 2004 were reviewed. For statistic analysis, the survival rate was determined using the Kaplan-Meier method with SPSS version 12.0, and the difference in survival rates was evaluated using a log-rank test. Results: The mean age of the patients with oral tongue SCC patients was 55 (19-85 years old). According to the T, N and pathologic stage, the patients were distributed from a higher to a lower incidence of cases, as follows: T2 (46.4%), T1 (37.9%), T4 (8.5%), and T3 (7.1%); N0 (65%), N1 (20.7%), N2 (13.6%), and N3 (0.7%); and stage Ⅰ (31.4%), stage Ⅱ (25.7%), stage Ⅳ (22.2%), and stage Ⅲ (20.7%). Local and regional recurrence and distant metastasis was present in 13.6%, 5% and 4.2% of patients, respectively. The five-year survival rate was 72.2%, and the prognostic factors for oral tongue SCC included neck metastasis, pathologic stage of the disease, cell differentiation, treatment modality, neck dissection as part of the treatment plan, and neck node recurrence. Discussion: It is suggested that ipsilateral neck dissection or bilateral neck dissection should be selected as a treatment of tongue SCC patients with advanced stage.

목차

Ⅰ. 서 론

Ⅱ. 연구대상 및 방법

Ⅲ. 결 과

Ⅳ. 고 찰

Ⅴ. 결 론

키워드

Squamous cell carcinoma Tongue neoplasms Mouth neoplasms Neoplasm staging Retrospective studies Survival rate