갑상선 절제술 후 발생하는 주관적인 음성 기능 저하의 위험 요인에 대한 연구

• 영문명: Risk Factors of Deteriorated Voice Quality in Patients Who Underwent Thyroidectomy
• 발행기관: 대한두경부종양학회
• 저자명: 이형신(Hyoung Shin Lee) 김성원(Sung Won Kim) 박찬우(Chan woo Park) 김창회(Chang Hoi Kim) 김서빈(Seo bin Kim) 임수진(Su jin Lim) 이강대(Kang Dae Lee)
• 간행물 정보: 『대한두경부종양학회지』제32권 제1호, 7~11쪽, 전체 5쪽
• 주제분류: 의약학 > 종양학
• 파일형태: PDF
• 발행일자: 2016.05.30

영문 초록

Background and Objectives: Quality of voice may be deteriorated after thyroidectomy without any injury to recurrent laryngeal nerve. While there have been several studies showing the change of acoustic parameters after thyroidectomy, factors related to deteriorated voice quality have been rarely studies. In this study, we sought to analyze the factors associated to deteriorated voice quality after thyroidectomy. Materials and Methods: We made a retrospective review of 35 patients who underwent thyroidectomy for papil-lary thyroid carcinoma. Voice analysis including acoustic analysis, voice handicap index 10 (VHI-10), and GRBAS score was conducted before and 3 months after surgery. Patients were grouped according to the amount of increase in VHI-10 after surgery ; group A (ΔVHI<7) and group B (ΔVHI≥7). Clinicopathologic factors associated to patients of group B were analyzed and changes of parameters from acoustic analysis in each group were evaluated. Results : Patients of group B were associated with age ≥ 45 years (p=0.025) and showed borderline association to total thyroidectomy (p=0.075) and tumor size ≥ 1cm (p=0.086). Multivariate analysis demonstrated that those with age ≥ 45 years were independently associated to deteriorated quality of voice (p=0.014, HR=18.38). Patients of group B were also associated to significant deterioration of high pitch (p<0.001) and Grade score with borderline significance (p=0.054). Conclusion: Patients older than 45 years may have higher risk of deterioration of quality of voice after thyroi-dectomy based on increase of VHI-10 score (ΔVHI≥7). Association with deterioration of high pitch should also be considered in these patients.

목차

Abstract

서론

대상 및 방법

결과

고찰

결론

References

키워드

갑상선암 갑상선 절제술 음성 음성장애지수 Papillary thyroid carcinoma Thyroidectomy Voice Voice handicap index