경부 림프절 종대로 발현한 원발 부위 불명의 전이암

• 영문명: Metastatic Carcinoma of an Unknown Primary Site Presented to the Neck
• 발행기관: 대한두경부종양학회
• 저자명: 김태용(Tae Yong Kim) 조요한(Yo Han Joh) 김진수(Jin Su Kim) 홍용상(Yong Sang Hong) 이근욱(Keun Wook Lee) 윤탁(Tak Yun) 송은기(Eun Ki Song) 나임일(Im Il Na) 신현춘(Hyun Chun Shin) 김동완(Dong Wan Kim) 이재서(Chae Seo RLee) 성명훈(Myung Whun Sung) 허대석(Dae Seog Heo) 김광현(Kwang Hyun Kim) 우홍균(Hong Gyun Wu) 김노경(Noe Kyeong Kim)
• 간행물 정보: 『대한두경부종양학회지』제20권 제2호, 181~188쪽, 전체 8쪽
• 주제분류: 의약학 > 종양학
• 파일형태: PDF
• 발행일자: 2004.11.30

영문 초록

Background: About 3% of all cancer patients suffer from cancer of unknown primary origin. Generally, carcinoma of unknown primary (CUP) carries a grave prognosis, but primary tumor presented to the neck is exception to this. The aims of study are to determine the role of chemotherapy and to find the prognostic factors in unknown primary tumor presented to the neck. Method and Material: Eighty-four patients were diagnosed with unknown primary tumor presented to the neck between January 1996 and June 2002. Among 84 patients, 43 patients (52%) received chemotherapy, radiation or surgery were performed in 20 patients (23%), 21 patients (25%) had no treatment. Results: The response rates to chemotherapy were 87.5% in CUP only localized to the neck and 44.0% in CUP systemically involved (p=0.012). A median follow-up duration was 6.4 years and overall median survival time was 9 months. The median overall survival time of patients treated with chemotherapy were 17 months and that of patients who received surgery or radiation were 20 months (p=0.3548). The important prognostic factors were performance status and the number of involved organ. Conclusion: The prognosis of patients with CUP presented to the neck is more favorable than that of patients with CUP of other localization. The effectiveness of chemotherapy for CUP only localized to the neck was similar to that of surgery or radiation. The important prognostic factors were performance status and the number of involved organ.

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원발부위불명 경부림프절전이 항암화악요법 병합요법 Unknown primary Cervical lymph node metastases Chemotherapy Combined therapy