아급성 괴사성 림프절염의 임상적 고찰

• 영문명: Clinical Study of Subacute Necrotizing Lymphadenitis
• 발행기관: 대한두경부종양학회
• 저자명: 추호석(Ho Suk Chu) 정은재(Eun Jae Jung) 우정수(Jeong Su Woo) 황순재(Soon Jae Hwang) 이흥만(Heung Man Lee)
• 간행물 정보: 『대한두경부종양학회지』제19권 제2호, 133~136쪽, 전체 4쪽
• 주제분류: 의약학 > 종양학
• 파일형태: PDF
• 발행일자: 2003.11.30

영문 초록

Background and Objectives: Kikuchi's disease or subacute necrotizing lymphadenitis is a cause of persistently enlarged lymph nodes unresponsive to antibiotic therapy. It affects predominantly young women under the age of 30, and it is seen primarily in the Asian population. Although this disease usually follows a benign course, all describing a clinical entity that has been mistaken for malignant lymphoma, lupus, and an assortment of infectious diseases. The purpose of this study is to report clinical characteristics and treatment outcome in order to contribute to the precise diagnosis and treatment. Materials and Methods: We reviewed 27 cases, who were diagnosed as subacute necrotizing lymphadenitis on excisional biopsy during the past 5 years from January 1998 to December 2002. Results: It occurred more often in females (20 cases ; 74%) than males (7cases ; 26%), and it was seen more frequently in the second and third decades (21 cases ; 78%). Cervical lymphadenopathy were usually multiple (24 cases, 89%) and measured less than 2cm (20 cases, 74%). The posterior cervical and deep jugular chains are the most common location(34 cases ; 81%). Leukopenia(18 cases, 67%) and elevated ESR(20 cases, 75%) were commonly noted in laboratory data. Conclusions: It is easy that Kikuchi's disease is mistaken for malignant lymphoma. So we should consider fine needle aspiration or open biosy of lymph node for histologic diagnosis in patients who have localized cervical lymphadenopathy unresponsive to antibiotic therapy.

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키워드

아급성 괴사성 림프절염 Kikuchi병 생검 Subacute necrotizing lymphadenitis Kikuchi's disease Biopsy