망막대동맥류에 합병된 황반부종에서 유리체강내 베바시주맙 주입술의 치료효과

• 영문명: Intravitreal Bevacizumab for Macular Edema Secondary to Ruptured Retinal Arterial Macroaneurysm
• 발행기관: 대한안과학회
• 저자명: 문상정 김상원 김호숭 강재훈 윤희성,Sang Jeong Moon, MD, Sang Won Kim, MD, Ho Soong Kim, MD, Jae Hoon Kang, MD, Hee Seong Yoon, MD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume53,number4, 522~527쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2012.04.15

영문 초록

Purpose: To study the short-term effect of intravitreal injection of bevacizumab in the treatment of macular edema secondary to retinal macroaneurysm. Methods: Eight eyes of 9 patients who underwent consecutive intravitreal bevacizumab injections for macular edema secondary to retinal macroaneurysm were prospectively evaluated. Complete eye examination including the best corrected visual acuity (BCVA), fundus examination and optical coherence tomography (OCT) were performed at baseline and follow- up visits at 2, 4 and 6 months. Results: The mean age was 73.6 ± 6.9 years, and the mean study period was 7.3 ± 2.6 months. At the final visit, BCVA improved from log MAR 1.92 ± 0.67 to log MAR 0.87 ± 0.57. The mean central macular thickness on OCT image decreased from 388 ± 168 μm at the initial visit to 200 ± 39 μm at the final visit. Three eyes without subretinal hemorrhage presented better visual outcome than eyes with subretinal hemorrhage. All eyes showed some decrease in angiographic leakage. No adverse side effects were observed following the injections. Conclusions: Intravitreal bevacizumab injection can be used as a selective alternative treatment modality for macular edema secondary to retinal macroaneurysm. J Korean Ophthalmol Soc 2012;53(4):522-527

키워드

Bevacizumab, Retinal macroaneurysm