데스메막박리 자동각막내피층판이식술 후 발생한 단순포진바이러스 각막염 1예

• 영문명: A Case of Herpes Simplex Keratitis after Descemet Stripping Automated Endothelial Keratoplasty
• 발행기관: 대한안과학회
• 저자명: 정세형 조재갑 윤경철,Se Hyeong Jeong, MD, Jae Kap Cho, MD, Kyung Chul Yoon, MD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume53,number3, 473~477쪽, 전체 5쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2012.03.15

영문 초록

Purpose: To report a case of herpes simplex keratitis after descemet stripping automated endothelial keratoplasty (DSAEK). Case summary: A 66-year-old male underwent DSAEK in his right eye due to bullous keratopathy after cataract surgery. The corneal epithelium which was removed during surgery was healed, but the patient was experiencing pain and decreased visual acuity in his right eye 1 month after surgery. Increasing corneal epithelial defects and corneal edema were observed on slit-lamp examination. Therapeutic soft contact lenses and artificial tears were used for treatment but were not effective, thus amniotic membrane transplantation was performed. Three months after transplantation, the epithelial defect appeared as a geographic ulcer suspecting to be herpes simplex keratitis; therefore, ganciclovir ophthalmic ointment and oral acyclovir were administered. Six months after antiviral therapy, the epithelial lesion of herpes simplex keratitis completely disappeared, leaving only mild corneal opacity. Conclusions: If corneal epithelial defects are persistent after DSAEK in patients even with no past history of herpes simplex keratitis, herpes simplex keratitis should be considered in the differential diagnosis. J Korean Ophthalmol Soc 2012;53(3):473-477

키워드

DSAEK, Ganciclovir, Herpes