혈액투석이 안압, 망막신경섬유층 두께 및 각막두께에 미치는 영향

• 영문명: The Effect of Hemodialysis on Intraocular Pressure, Retinal Nerve Fiber Layer Thickness and Corneal Thickness
• 발행기관: 대한안과학회
• 저자명: 강용석 황영훈 김재석 이주화,Yong Seok Kang, MD, Young Hoon Hwang, MD, Jae Suk Kim, MD, Joo Hwa Lee, MD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume53,number11, 1657~1662쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2012.11.15

영문 초록

Purpose: To compare the intraocular pressure (IOP), retinal nerve fiber layer (RNFL) thickness and central corneal thickness (CCT) in healthy individuals and patients with chronic renal failure (CRF) undergoing hemodialysis, and to evaluate the changes in each parameter before and after hemodialysis in patients with CRF. Methods: Thirty-six eyes of 36 patients with CRF undergoing hemodialysis were included in the hemodialysis group and 54 eyes of 54 healthy subjects were recruited as the control group. All subjects underwent a complete eye examination, including best-corrected visual acuity (BCVA), slit lamp examination, dilated funduscopic examination, gonioscopy, automated perimetry, IOP measurement, corneal pachymetry, and evaluation of RNFL thickness. In the hemodialysis group, IOP, RNFL thickness, and CCT were measured again within 1 hour of hemodialysis. Results: Age, sex, BCVA, cup-to-disc ratio, IOP, and CCT were not statistically different between the 2 groups. The RNFL of the hemodialysis group was statistically significantly thinner than the control group (p < 0.001). The IOP decreased from 16.52 ± 2.95 mm Hg to 14.88 ± 2.03 mm Hg after hemodialysis (1.63 ± 3.27 mm Hg; p = 0.005). The changes in RNFL thickness and CCT were not statistically significant (p = 0.148, p = 0.352). Conclusions: In CRF patients with hemodialysis, RNFLs were thinner in the control group and hemodialysis induced significant IOP reduction. The results from the present study should be considered for the proper evaluation of ocular disorders in CRF patients with hemodialysis.

키워드

Central corneal thickness, Chronic renal failure, Hemodialysis, Intraocular pressure, Retinal nerve fiber layer thickness