호르몬 대체요법과 안 질환: 제4기 국민건강영양조사자료

• 영문명: Hormone Replacement Therapy and Eye Diseases: KNHANES IV
• 발행기관: 대한안과학회
• 저자명: 임형택 박선영 윤진숙,Hyung Taek Rim, MD, Sun Young Park, MD, Jin Sook Yoon, MD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume53,number10, 1445~1450쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2012.10.15

영문 초록

Purpose: To identify the association between hormone replacement therapy and eye diseases. Methods: The fourth Korea National Health and Nutrition Examination Survey (KNHANES IV) is a nationwide survey. The study included 5,808 females who completed the KNHANES IV. The prevalence of eye disease of adjusted mean using linear regression analysis between the subjects who had hormone replacement therapy and those who did not have the therapy was analyzed. Results: Among the 5,808 females, 480 (8.3%) received hormone replacement therapy. The adjusted prevalence of myopia was 44.5% (95% CI, 38.1-51.2) in the subjects who received hormone replacement therapy, and 54.4% (95% CI, 52.6-56.1) in those who did not have the therapy. The adjusted prevalence of hyperopia was 7.7% (95% CI, 5.5-10.6) in subjects who received hormone replacement therapy and 4.5% (95% CI, 3.8-5.3) in those who did not have the therapy. The adjusted prevalence of pterygium was 2.1% (95% CI, 1.3-3.3) in the subjects who received hormone replacement therapy and 3.3% (95% CI, 2.7-4.0) in those who did not have the therapy. All the results were statistically significant with a p-value <0.05. The adjusted prevalence of diabetic retinopathy was 5.6% (95% CI, 1.4-19.8) in the subjects who received hormone replacement therapy and 16.7% (95% CI, 13.0-21.2) in those who did have the therapy. The p-value was 0.053, which is marginally statistically significant. Conclusions: The adjusted prevalence of myopia, pterygium, and diabetic retinopathy in the subjects who received hormone replacement therapy was low, although hyperopia was statistically significantly high. J Korean Ophthalmol Soc 2012;53(10):1445-1450

키워드

Eye diseases, Hormone replacement therapy, KNHANES IV, Socio-demographic factors