3차병원을 방문한 플릭텐각결막염 환자의 임상양상 분석

• 영문명: Analysis of Clinical Characteristics in Phlyctenular Keratoconjunctivitis at a Tertiary Center
• 발행기관: 대한안과학회
• 저자명: 조동현 김미금 위원량 이진학 ,Dong Hyun Jo, MD,, Mee Kum Kim, MD, PhD,, Won Ryang Wee, MD, PhD,, Jin Hak Lee, MD, PhD,,
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume52,number1, 7~13쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2011.01.15

영문 초록

Purpose: To report the clinical characteristics of patients with phlyctenular keratoconjunctivitis at a tertiary care center in Korea. Methods: The authors of the present study retrospectively reviewed the medical records of 26 patients who were diagnosed with phlyctenular keratoconjunctivitis, identifying the age and sex at diagnosis, diagnosis of the referring clinic, laterality and location of the lesions, the results of bacterial cultures from the meibum, and treatment options. Results: Eighteen patients (76.2%) were female, and the mean age at diagnosis was 18.4 ± 10.5 years. Nine patients (34.6%) showed evidence of bilateral diseases, and corneal lesions were observed in 27 eyes of 21 patients. Bacterial cultures from the meibum were performed for 17 patients, with the following results: 6 cases of Staphylococcus epidermidis, 4 cases of Corynebacterium species, and 1 case of Propionibacterium acne. Neovascularization with corneal phlyctenules occurred from the inferior quadrant mostly. Twenty-four patients received the remission treatment of prednisolone acetate 1% eye drops and evidence of regression of new vessels was observed in all patients. Three patients (16.7%) experienced recurrence despite the maintenance treatment of cyclosporine 0.05% eye drops. Visual acuities improved significantly after the remission treatment, as compared to the initial visit. Conclusions: The phlyctenular keratoconjunctivitis patients who visited the tertiary center in Korea showed similar findings regarding demographics, involvement of blepharitis, and identified microorganisms, as compared with patients in previous reports. However, corneal lesions involving the visual axis were frequent, suggesting that with proper diagnosis and treatment, improvement in visual acuities is possible. J Korean Ophthalmol Soc 2011;52(1):7-13

키워드

Blepharitis, Cornea, Keratoconjunctivitis, Korean, Phlyctenular keratitis