당뇨황반부종에서 망막두께분석기로 측정한 망막두께와 다국소망막전위도의 반응의 연관성

• 영문명: A Correlation with Retinal Thickness Using Retinal Thickness Analyzer and the Responses of Multifocal Electroretinogram in Patients with Diabetic Macular Edema
• 발행기관: 대한안과학회
• 저자명: 성미선 박태관 이정희 온영훈,Mi Sun Sung, M.D., Tae Kwann Park, M.D., Jeong Hee Lee, M.D., Young Hoon Ohn, M.D.
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume47,number9, 1401~1409쪽, 전체 9쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2006.09.30

영문 초록

Purpose: To assess the correlation between retinal thickness determined with a retinal thickness analyzer (RTA) and the responses of multifocal electroretinogram (mfERG) in patients with diabetic macular edema. Methods: RTA and mfERG were performed in patients with diabetic macular edema (20eyes, 10 patients) and normal subjects (10eyes, 10 patients). The measured retina of RTA and mfERG overlapped based on the anatomical landmarks of the fundus. The center of macula was defined as “Area 1”, and the central 5 degree retina including the center of macula was defined as “Area 2”. The correlations between retinal thickness and the local responses in each area were assessed. Results: The mean retinal thickness of patients with diabetic macular edema was significantly greater than that of normal subject, and the results of mfERG typically represented decreased amplitudes and delayed latencies. In the matching of retinal thickness and local responses in Area 2, amplitudes of N1 & P1 decreased and latency of P1 delayed as the retinal thickness increased. The correlation was prominent in patients with diabetic macular edema. Conclusions: In the matching of RTA and mfERG of patients with diabetic macular edema, retinal thickness and local responses were significantly correlated.

키워드

Diabetic macular edema, Local responses, Multifocal ERG, Retinal thickness, RTA.