양막이식술과 보조적인 마이토마이신 C의 사용에 의한 검구유착의 치료

• 영문명: Amniotic Membrane Transplantation and Use of Adjunctive Mitomycin C in the Treatment of Symblepharon
• 발행기관: 대한안과학회
• 저자명: 김덕재 윤경철 박영걸,Dok-Jae Kim, M.D., Kyung-Chul Yoon, M.D., Yeoung-Geol Park, M.D.
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume46,number7, 1108~1113쪽, 전체 6쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2005.07.31

영문 초록

Purpose: To evaluate the effectiveness of amniotic membrane transplantation and adjunctive mitomycin C in the treatment of symblepharon. Methods: Amniotic membrane transplantation was performed and adjunctive mitomycin C was applied in 7 patients with symblepharon, resulting from various causes. Mitomycin C soaking (0.02%, 5 minutes) was used intraoperatively followed by meticulous dissection of adherent tissue. Next, amniotic membrane transplantation was done with 2 layers of removed conjunctival tissue and a silicone band bolster was applied to the reconstructed fornix. Evaluating factors were the depth of reconstructed fornix, limitation of eyeball movement, recurrence and presence of complication. These factors were checked at the last visit. Results: Mean follow-up period was 9.0×±A 4.54 months and all patients showed reconstructed fornix. Six patients showed successful outcome (depth of fornix ?? 8 mm) and one patient showed 6 mm of forniceal depth and mild limitation of gaze. Conclusions: Treatment of symblepharon by amniotic membrane transplantation and adjunctive mitomycin C administration can reduce the recurrence rate of symblepharon without complication.

키워드

Amniotic membrane transplantation, Mitomycin C, Symblepharon