병적 근시와 동반된 맥락막 신생혈관에서 광역학 치료의 임상 적용

• 영문명: Photodynamic Therapy in Practice: A Review of Experiences with Myopic CNV in Korean Patients
• 발행기관: 대한안과학회
• 저자명: 정은지 오현섭 고형준 이성철 권오웅,Eun-Jee Chung, M.D., Hyun-Sub Oh, M.D., Hyoung-Jun Koh, M.D., Sung-Chul Lee, M.D., Oh-Woong Kwon, M.D.
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume46,number4, 664~670쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2005.04.30

영문 초록

Purpose: To evaluate the effects of photodynamic therapy with verteporfin on visual acuity and fluorescein angiography in choroidal neovascularization (CNV) associated with pathologic myopia and to determine if this treatment could reproduce the results achieved in the Verteporfin in Photodynamic Therapy (VIP) Trial in Korean patients. Methods: Forty-two eyes of 39 patients with CNV secondary to pathologic myopia were included. A retrospective review of their clinical records and fluorescein angiography was done. The patients underwent photodynamic therapy with verteporfin and were followed up for more than 6 months after the therapy. The change in best corrected visual acuity (BCVA) and leakage in fluorescein angiography were evaluated. Results: The mean age of the patients was 39.6 and mean follow-up period was 23.5 months. The BCVA of the patients improved in 22 (52.4%) eyes, was unchanged in 13 (30.9%), and worsened in 7 (16.7%). The leakage in fluorescein angiography decreased in 25 (59.5%) eyes. Conclusions: Photodynamic therapy with verteporfin for myopic CNV in Korean patients appeared to be effective in stabilization of the lesions and improvement of visual acuity.

키워드

Choroidal neovascularization (CNV), Pathologic myopia, Photodynamic therapy (PDT)