한쪽 엽에 국한된 고분화 갑상선암에서 갑상선 엽절제술의 의의

• 영문명: Thyroid Lobectomy for Treatment of Well Differentiated Thyroid Cancer Confined to One Lobe
• 발행기관: 대한내분비외과학회
• 저자명: 김유석 김권천 Yoo Seok Kim Kweon Cheon Kim
• 간행물 정보: 『The Koreran journal of Endocrine Surgery』13권2호, 83~86쪽, 전체 4쪽
• 주제분류: 의약학 > 일반외과학
• 파일형태: PDF
• 발행일자: 2013.06.30

영문 초록

Purpose: There has been controversy of the lobectomy for well differentiated thyroid cancer (WDTC). Current guidelines recommend total thyroidectomy for the cancer over 1cm, despite previous report suggesting that the lobectomy provides similar excellent outcomes. The purpose of our study is to report our experience of WDTC treated by thyroid lobectomy. Methods: We retrospectively analyzed 284 patients with WDTC treated by thyroid lobectomy at department of Surgery in Chosun University Hospital from January 2002 to December 2010. Overall survival (OS) and disease-free survival (DFS) were determined by the Kaplan-Meier method. Factors predictive of recurrence by univariate and multivariate analysis were determined using the ՗² test and Cox proportional hazard model respectively. Results: With a mean follow-up of 60.4 months, OS and RFS for all patients were 97.9% and 96.5% respectively. No patient died due to WDTC. Univariate analysis showed statistically significant differences in recurrence by tumor size (P=0.013) and presence of invasion (P=0.039). However, Multivariate analysis showed no significant difference in local recurrence. Conclusion: Patients with WDTC confined to one lobe can be safely treated by lobectomy.

키워드

갑상선암, 갑상선 엽절제술, 국소재발,Thyroid cancer, Thyroid lobectomy, Local recurrence