국소 진행성 갑상선암의 치료

• 영문명: Treatment of Locally Advanced Thyroid Cancer
• 발행기관: 대한내분비외과학회
• 저자명: 장항석 장호진 Hang-Seok Chang Hojin Chang
• 간행물 정보: 『The Koreran journal of Endocrine Surgery』13권2호, 71~76쪽, 전체 6쪽
• 주제분류: 의약학 > 일반외과학
• 파일형태: PDF
• 발행일자: 2013.06.30

영문 초록

Thyroid cancer is an indolent condition that usually presents as a limited disease in the neck. Invasion to vital organs is rarely observed; however, it can be a major cause of mortality, even in well-differentiated thyroid cancers. The common sites of local invasion are strap muscle, recurrent laryngeal nerve, laryngo-tracheal tree, esophagus, and great vessels in the lateral compartment and mediastinum. Uncontrolled invasion to vital organs in the neck and mediastinum can cause significant morbidity and affect quality of life and survival. Limited involvement of the aero-digestive tract can be controlled by conservative surgical treatments such as shaving-off procedures, while radical resection and subsequent reconstructive procedures are the best choice for more serious cases. In planning the treatment, the risk-benefit ratio should be carefully evaluated to reduce the morbidity, as well as achieve maximal therapeutic effects. Postoperative adjuvant therapies have been the subject of controversy, but there is a general consensus, especially for high-risk patients, that radioiodine therapy and TSH suppression after radical resection are beneficial. The benefits of external beam radiation therapy are unclear, but it should be considered in patients with microscopic residual disease. In conclusion, radical eradication of lesions followed by proper adjuvant therapy is the treatment of choice for locally advanced thyroid cancers.

키워드

국소진행성 갑상선암, 광범위 절제술, 국소 절제술, 재건술, 수술 후 보조요법,Locally advanced thyroid cancer, Radical resection, Limited resection, Operative morbidity, Postoperative adjuvant therapy