Carcinoma Showing Thymus Like Differentiation (CASTLE) 1예 대한 경험

• 영문명: Carcinoma Showing Thymus Like Differentiation (CASTLE): A Case Report
• 발행기관: 대한내분비외과학회
• 저자명: 김종현 박근명 김세중 조영업 주영채¹ Jong Hyun Kim M.D. Keun Myung Park M.D. Sei Joong Kim M.D. Ph.D. Young Up Cho M.D. Ph.D. and Young Chae Chu M.D. Ph.D.¹
• 간행물 정보: 『The Koreran journal of Endocrine Surgery』11권4호, 292~296쪽, 전체 5쪽
• 주제분류: 의약학 > 일반외과학
• 파일형태: PDF
• 발행일자: 2011.12.30

국문 초록

Carcinoma showing thymus-like differentiation (CASTLE) is a very rare malignant neoplasm of the thyroid, which resembles lymphoepithelioma or squamous cell carcinoma of the thymus. It originates from ectopic thymic tissue or remnants of the branchial pouches. We recently experienced a case of CASTLE in the thyroid gland of a 65-year-old woman. The patient presented with a non-tender mass in the right thyroid gland and dyspnea and coughing upon bending. The patient was diagnosed with 'cystic change of adenomatous goiter' of the thyroid by fine needle aspiration cytology. Right thyroidectomy was performed because of nodular hyperplasia on frozen biopsy. Histologic examination of the resected tumor showed that the tumor was lobulated and expansive growth pattern, with fibrous septa dividing the tumor and infiltrated by lymphocytes and plasma cells. Tumor cells possessed oval, large vesicular nuclei and prominent nucleoli, and the immunohistochemical staining was positive for CD5. The patient was diagnosed with thyroid CASTLE. We performed complete thyroidectomy. There has been no local regional recurrence. (Korean J Endocrine Surg 2011;11:292-296)

키워드

흉선, 갑상선샘, 갑상선절제술,Thymus, Thyroid gland, Thyroidectomy