갑상선에서 발생한 과립세포종양 1예 보고

• 영문명: Granular Cell Tumor of Thyroid Gland That Was Concomitant with Papillary Thyroid Carcinoma - A Case Report
• 발행기관: 대한내분비외과학회
• 저자명: 장은정 서안나 이선재 박지영 Eun Jeong Jang M.D. An Na Seo M.D. Sun-Jae Lee M.D. and Ji-Young Park M.D. Ph.D.
• 간행물 정보: 『The Koreran journal of Endocrine Surgery』11권1호, 28~30쪽, 전체 3쪽
• 주제분류: 의약학 > 일반외과학
• 파일형태: PDF
• 발행일자: 2011.03.30

영문 초록

Granular cell tumor (GCT) of the thyroid is rare and histogenesis of the carcinoma still remains poorly understood. Here in this study, we report a case of perithyroidal granular cell tumor in a 44-year-old woman, diagnosed as medullary carcinoma upon the interoperative frozen diagnosis. The tumor was comprised of white, solid mass with infiltrating margin in isthmus. Microscopically, the tumor revealed abundant eosinophilic cytoplasm, elongated nucleus and eosinophilic amyloid-like materials. It was composed of diffuse sheets of polygonal cells with abundant eosinophilic cytoplasm and cytologically bland nucleus on permanent section. On immunohistochemical staining, S-100 and CD68 are diffusely positive. Determining the progression and the behavior of the tumor is critical for providing long-term management and preventing aggressive treatment. (Korean J Endocrine Surg 2011;11:28-30)