미세유두상갑상선암의 갑상선 절제 범위

• 영문명: Surgical Extent of Thyroidectomy for Papillary Thyroid Microcarcinoma
• 발행기관: 대한내분비외과학회
• 저자명: 홍석준 Suck Joon Hong M.D.
• 간행물 정보: 『The Koreran journal of Endocrine Surgery』11권1호, 1~11쪽, 전체 11쪽
• 주제분류: 의약학 > 일반외과학
• 파일형태: PDF
• 발행일자: 2011.03.30

영문 초록

The incidence of PTMC (papillary thyroid microcarcinoma) has rapidly increased recently due to the application of ultrasonography to the thyroid. The good prognosis of PTMC is well known with a mortality rate of less than 1%. However, there is controversy about the surgical extent of thyroidectomy for PTMC patients between surgeons and endocrinologists due to differences in understanding the clinical properties of PTMC, while having a difference in basic concepts in the treatment and follow up strategy for PTMC patients. Total thyroidectomy is recommended for PTMC patients because there is no major difference in the rate of lymph node metastasis, extrathyroidal extension, multiplicity between the PTMC and PTC over 1 cm in size and although rare, occasional distant metastasis and mortality cases could be developed. However, there is no evidence of benefit of total thyroidectomy for the survival rate of PTMC patients. The microscopic lymph node metastasis and extrathyroidal extension are not prognostic factors for the survival or recurrence in PTMC. The clinical lateral neck lymph node metastasis and multiplicity has been proposed as valuable prognostic factors in micropapillary carcinoma and these factors could be assessed accurately by ultrasonography preoperatively. A decision on the proper extent of thyroidectomy could be possible in most PTMC patients. This article summarizes available data and concludes that routine total thyroidectomy for PTMC patients is not rational. (Korean J Endocrine Surg 2011;11:1-11)

키워드

미세유두상갑상선암, 갑상선 절제, 절제 범위, 예후인자,Papillary thyroid microcarcinoma, Thyroidectomy, Surgical extent, Prognostic factors