갑상선 결절 환자에서 혈청 갑상선자극호르몬 수치와 고분화 갑상선암과의 연관성에 관한 분석

• 영문명: Preoperative Thyroid-stimulating Hormone Levels as a Predictor of Thyroid Carcinoma
• 발행기관: 대한내분비외과학회
• 저자명: 정성엽 김훈엽 류우상 우상욱 손길수 이재복 배정원 Sung Yup Joung Hoon Yub Kim Woo Sang Ryu Sang Uk Woo Gil Soo Son Jae Bok Lee and Jeoung Won Bae
• 간행물 정보: 『The Koreran journal of Endocrine Surgery』10권4호, 220~223쪽, 전체 4쪽
• 주제분류: 의약학 > 일반외과학
• 파일형태: PDF
• 발행일자: 2010.12.30

영문 초록

Purpose: This study investigated the effects of serum thyroid-stimulating hormone (TSH) levels in predicting malignancy-associated differentiated thyroid cancer (DTC) and benign thyroid nodules. Methods: Between January 2005 and December 2007, 346 patients underwent thyroid surgery at one hospital. Their records were retrospectively reviewed. Results: Sixty-nine percent (237 of 346) of the patients had DTC. The mean preoperative TSH level was higher than in the malignant group (5 uIU/ml vs 0.4 uIU/ml). The rate of malignancy was the 71% in patients with TSH levels ＞5 uIU/ml. The TSH level of DTC with metastasis of the lymph node was higher than that with non-metastasis (3.08 uIU/ml vs 2.09 uIU/ml, P＜0.01) Conclusion: The likelihood of DTC increases with higher serum TSH concentration. Serum TSH level might be useful in predicting malignant nodular thyroid lesion. (Korean J Endocrine Surg 2010;10:220-223)

키워드

갑상선암, 갑상선자극호르몬, 분화갑상선암,Thyroid carcinoma, Thyroid stimulating hormone, Differentiated thyroid cancer