고압맥동 평류자극이 가토 상처치유에 미치는 영향

• 영문명: Effect of High Voltage Pulsed Galvanic Current on Wound Healing in Rabbits
• 발행기관: 한국전문물리치료학회
• 저자명: 김식현(Kim Sik-hyun) 박래준(Park Rae-joon) 권혁철(Kwon Hyuk-cheol)
• 간행물 정보: 『한국전문물리치료학회지』한국전문물리치료학회지 제3권 제3호, 67~81쪽, 전체 15쪽
• 주제분류: 의약학 > 의학일반
• 파일형태: PDF
• 발행일자: 1996.12.31

영문 초록

This study was performed to assess the efficacy of high voltage pulsed galvanic current for the healing of wounds in rabbits. Skin wounds were created laterally on the flank of 12 domestic rabbits(3×3 cm). The wounds of each group were treated with an intensity of 170 V at a frequency of 70 pulses per second, which was applied for 30 minutes a day for 10 days. The experimental groups were randomly assigned to either EXPⅠ(n=3), EXPⅡ(n=3), EXPⅢ(n=3) or control(n=3). Each group was stimulated under the following conditions : 1) EXPⅠ(Negative polarity), 2) EXPⅡ(Change in polarity, negative electrode stimulation during the first 3 days and then positive electrode stimulation from 4 to 10 days), 3) EXPⅢ(Positive polarity), 4) control(No stimulation). An active electrode was placed over the wound and a dispersive electrode on the buttock. The rate of wound closure was compared with the original wound size, evaluated by a tracing film in each measurement period. Finally, on the wound in each group, skin tissue was excised for histological evaluation after treatment for 10 days. The results obtained are as follows : 1) It was found that the control group did not show a complete remodeling of epitherial layer and had a chronic inflammatory response. Judging from the irregularity of intercellular space and the loose alignment of connective tissue, these findings show that wound healing was delayed. 2) EXPⅠ showed a significant bactericidal effect, but a moderate response of vasodilation. The rate of wound closure was slower when compared with EXP II, III. 3) EXPⅡ showed a complete remodeling of epitherial layer and a positive repair of connective tissue. Its rate of wound closure was best when compared with the others. 4) EXPⅢ had a slower rate of wound closure than EXPⅡ, but judging from the greater proliferation of collagen fibers and the dense alignment of connective tissue, this positive electrode was very effective in the formation of neo - connective tissue.

목차

Abstract

Ⅰ. 서론

Ⅱ. 재료 및 방법

Ⅲ. 결과

Ⅳ. 고찰

Ⅴ. 결론

인용문헌

키워드

High voltage pulsed galvanic current Skin wound Wound healing