상악동암의 방사선 치료

• 영문명: Radiation Therapy of Maxillary Sinus Cancer
• 발행기관: 대한방사선종양학회
• 저자명: 이혜경(Hae Kyung Lee) 강진오(Jin Oh Kang) 홍성언(Seong Eon Hong)
• 간행물 정보: 『대한방사선종양학회지』제12권 제3호, 307~313쪽, 전체 7쪽
• 주제분류: 의약학 > 종양학
• 파일형태: PDF
• 발행일자: 1994.11.30

영문 초록

Purpose : Maxillary sinus cancers usually are locally advanced and involve the structures around sinus. It is uncommon for this cancer to spread to the regional lymph nodes. For this reason local control is of paramount important for cure. A policy of combined treatment is generally accepted as the most effective means of enhancing cure rartes. This paper reports our experience of a retrospective study of 31 patients treated with radiation therapy alone and combination therapy of surgery and radiation. Materials and Methods : Between July 1974 and January 1992 47 patients with maxillary sinus cancers underwent either radiation therapy alone or combination therapy of surgery and radiation. Of these only 31 patients were eligible for analysis. The distribution of clinical stage by the AJCC system was 26%(8/31) for T2 and 74%(23/31) for T3 and T4. Eight patients had palpable lymphadenopathy at diagnosis. Primary site was treated by Cobalt-60 radiation therapy using through a 45 wedge-pair technique. Elective neck irradiation was not routinely given. Of these 8 patients the six who had clinically involved nodes were treated with definite radiation therapy. The other two patients had received radical neck dissection. The twenty-two patients were treated with radiation alone and 9 patients were treated with combination radiation therapy. The RT alone patients with RT dose less than 60 Gy were 9 and those above 60 Gy were 13. Results : The overall 5 year survival rate was 23.8%. The 5 year survival rate by T-stage was 60.5% and 7.9% for T2 and T3, 4 respectively. Statistical significance was found by T-stage(p<0.005). The 5 year survival rate by N-stage was 30% for N(-) and 8.3% for N(+), but statistically no significant difference was seen(p≥0.1). The 5 year survival rate for RT alone and combination RT was 22.5% and 27.4% respectively. The primary local control rate was 65%(20/31). Conclusion : This study did not show significant difference in survival between RT alone and combination RT. There is still much controversy with regard to which treatment is optimum. Improved RT technique and development of multimodality treatment are essential to improve the local control and the survival rate in patients with advanced maxillary sinus cancer.

키워드

Paranasil sinus tumor Maxillary sinus cancer Radiation therapy