소나무추출물인 로진에 대한 단회경피독성 평가

• 영문명: Single-dose dermal toxicity test on Rosin？？ from an extract of Pine tree
• 발행기관: 한국인체미용예술학회
• 저자명: 황석연(Seock Yeon Hwang) 이혜숙(Hye Sook Lee)
• 간행물 정보: 『한국인체미용예술학회지』한국인체예술학회지 제10권 제3호, 75~83쪽, 전체 9쪽
• 주제분류: 예술체육 > 예술일반
• 파일형태: PDF
• 발행일자: 2009.09.30

영문 초록

There has been a great deal of interest in the applications of plant-based extracts to both cosmetic and medicinal industries. The aim of this study was to evaluate the single-dose dermal toxicity test on Rosin？？ from an extract of Pine tree which is well-known as a very powerful antioxidant, anti-inflammatory, and antibiotic material according to the guidelines of Korea Food and Drug Administration. Total of 80 rats(40 female rats and 40 male rats) were divided into 4 groups: control(vehicle(80% ethanol)), Rosin？？ 1%(in 80% ethanol), Rosin？？ 5% and Rosin？？ 10 %, which was used for the test of dose toxicity. There were no clinical signs and pathological changes compared with control group. Body weights were not significantly changed between control and Rosin？？ treatment groups. The result of this study indicated that Rosin？？ was able to be used for Atopy Dermatitis to 10% and it is a safe material to skin without skin irritation or allergic sensitization.

목차

Abstract

Ⅰ. 서론

Ⅱ. 재료 및 방법

Ⅲ. 결과 및 고찰

참고문헌

키워드

Rosin？？(로진) Pine tree(소나무) Single-dose dermal toxicity(단회경피독성평가) Atopy Dermatitis(아토피피부염)