국내 학령전기 아동의 예방접종력에 따른 홍역ㆍ유행성이하선염 항체양성률

• 영문명: Seroprevalence of measles and mumps antidody among preschool children in Korea, according to their vaccination history
• 발행기관: 한국역학회
• 저자명: 이정화(Jung-Hwa Lee) 배근량(Geun-Ryang Bae) 박창식(Chang-Sik Park) 정윤석(Yoon-Seok Chung) 강영아(Young-A Kang) 한현우(Hyun-Woo Han) 강춘(Chun Kang)
• 간행물 정보: 『한국역학회지』韓國疫學會誌 第30卷 第1號, 34~40쪽, 전체 7쪽
• 주제분류: 의약학 > 면역학
• 파일형태: PDF
• 발행일자: 2008.06.30

영문 초록

  Purpose: To maintain measles elimination status, we evaluated the seropositivity of measles and mumps according to time interval since the first or second dose of MMR in children aged 4 to 6 years, who are starting communal life.
  Materials and method: 2,447 children aged 4 to 6 years were enrolled at 251 public health centers over the period of March to May 2007. Subjects were verified their date of MMR vaccination and then their blood was sampled for serologic test. Measles and mumps IgG antibody was tested by ELISA at Korea CDC.
  Results: Vaccination coverage was 99.9% in the first dose, 64.9% in the second dose regardless of gender. Seropositivity of measles and mumps was 95.7%, 85.5% in the first dose and 98.7%, 98.1% in the second dose, respectively. The seropositivity of measles was 88.1% in 6-year-olds who did not receive the second dose of MMR. As time since receipt, seropositivity of measles tended to decrease over time and was 93.3% in vaccinees over 48 months after the first dose.
  Conclusion: A first dose MMR at 12-15 months cannot lead to herd immunity. More public information is needed to encourage second dose vaccination before admission to day-care center or kindergarten.

목차

서론
조사대상 및 방법
연구결과
고찰
감사의 글
참고문헌
Abstract

키워드

Measles Mumps MMR Vaccine Seroepidemiologic Studies Herd Immunity