한국인 흡연과 사망위험에 대한 11년 추적연구

• 영문명: Smoking and cause of death in Korea : 11 years follow-up prospective study
• 발행기관: 한국역학회
• 저자명: 지선하(Sun-Ha Jee) 조인호(In-Ho Jo) 윤지은(Ji-Eun Yun) 박정용(Jung-Yong Park) 설재웅(Jae-Woong Sull) 오희철(Hee-Choul Ohrr) 이상이(Sang-Vi Lee) 윤유식(Yoo-Sik Yoon) Jonathan M Samet, 김일순(II-Soon Kim)
• 간행물 정보: 『한국역학회지』한국역학회지 제27권 제1호, 182~190쪽, 전체 9쪽
• 주제분류: 의약학 > 면역학
• 파일형태: PDF
• 발행일자: 2005.06.01

영문 초록

Objective : In Korea, male smoking prevalence is among the world's highest and mortality rates from smoking-caused cancers, particularly lung cancer, are escalating. This cohort study examined the effects of cigarette smoking on the risk of mortality from all causes, cancers and cardiovascular diseases(CVD), and characterized the relationship of the risk with the amount and duration of cigarette smoking. Method : A eleven-year prospective cohort study was carried out of on 1,207,592 Koreans, 30 to 95 years of age. The study population includes participants in a national insurance program, who completed a questionnaire on smoking and other risk factors. The main outcome measures were death from all causes, cancer and CVD, obtained through record linkage. At baseline, 482,997 men(60.0%) and 19,755(5.3%) women were current cigarette smokers. Results : In multivariate Cox proportional hazards models, controlling for age, alcohol drinking, exercise, and obesity, current smoking among men increased the risks of mortality from all cause death (relative risk[RR], 1.56; 95% confidence interval[CI], 1.52~1.59), all cancer (1.75, 1.68~1.82), and CVD(1.46, 1.38~1.55). Similar results were found for mortality among women. Smoking also increased the risks of mortality for cancer of the lung(4.60, 4.09~5.33) and other cancers, including larynx, bile duct, esophagus, liver, stomach, pancreas, bladder, and also leukemia. Current smoking among women increased the risk of lung cancer mortality(RR=2.83, 95% CI 2.38~3.36). Conclusion : In Korea, smoking is an independent risk factor for death from all causes, CVD and a number of major cancers. The findings affirm the need for aggressive tobacco control in Korea in order to minimize the epidemic of smoking-caused disease.

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참고문헌

Abstract