학술논문
Precision proteomics with TurboID: mapping the suborganelle landscape
이용수 0
- 영문명
- 발행기관
- 대한생리학회-대한약리학회
- 저자명
- Han Byeol Kim Kwang-eun Kim
- 간행물 정보
- 『The Korean Journal of Physiology & Pharmacology』제28권 제6호, 495~501쪽, 전체 7쪽
- 주제분류
- 의약학 > 의학일반
- 파일형태
- 발행일자
- 2024.11.01
4,000원
구매일시로부터 72시간 이내에 다운로드 가능합니다.
이 학술논문 정보는 (주)교보문고와 각 발행기관 사이에 저작물 이용 계약이 체결된 것으로, 교보문고를 통해 제공되고 있습니다.
국문 초록
Recent research underscores the pivotal role of cellular organelles, such as mitochondria, the endoplasmic reticulum, and lysosomes, in maintaining cellular homeostasis. Their dynamic interactions are critical for metabolic regulation and stress response. Analysis of organelle proteomes offers valuable insights into their functions in both physiology and disease. Traditional proteomic approaches to studying isolated organelles are now complemented by innovative methodologies focusing on inter-organelle interactions. This review examines the integration of advanced proximity labeling technologies, including TurboID and split-TurboID, which address the inherent limitations of traditional techniques and enable precision proteomics of suborganelle compartments and inter-organellar contact sites. These innovations have led to discoveries regarding organelle interconnections, revealing mechanisms underlying metabolic processes such as cholesterol metabolism, glucose metabolism, and lysosomal repair. In addition to highlighting the advancements in TurboID applications, this review delineates the evolving trends in organelle research, underscoring the transformative potential of these techniques to significantly enhance organelle-specific proteomic investigations.
영문 초록
목차
INTRODUCTION
SINGLE ORGANELLE
ORGANELLE CONTACT
CONCLUSION
REFERENCES
해당간행물 수록 논문
- Protective effect of 6′-Sialyllactose on LPS-induced macrophage inflammation via regulating Nrf2-mediated oxidative stress and inflammatory signaling pathways
- Precision proteomics with TurboID: mapping the suborganelle landscape
- Exercise improves muscle mitochondrial dysfunction-associated lipid profile under circadian rhythm disturbance
- Salidroside attenuates sepsis-induced acute lung injury by inhibiting ferroptosis-dependent pathway
- Chemopreventive potential of goniothalamin in diethylnitrosamine-induced hepatocellular carcinoma through the suppression of P13K/AKT signalling pathway
- Hemin attenuates bleomycin-induced lung fibrosis in mice by regulating the TGF-β1/MAPK and AMPK/SIRT1/PGC-1α/HO-1/ NF-κB pathways
- Predicting antioxidant activity of compounds based on chemical structure using machine learning methods
- Norepinephrine triggers glutamatergic long-term potentiation in hypothalamic paraventricular nucleus magnocellular neuroendocrine cells through postsynaptic β1-AR/PKA signaling pathway in vitro in rats
참고문헌
관련논문
의약학 > 의학일반분야 BEST
- 간호대학생의 인공지능 활용 간호수행 자신감에 영향을 미치는 요인
- 지역사회 인지저하 전·후기 노인의 건강 및 돌봄 요구 실태
- 국내 의료기관의 환자안전사고 관련 요인 분석: 2019-2022년 환자안전보고 데이터 활용 이차분석 연구
의약학 > 의학일반분야 NEW
- Erratum: Experiences of community-dwelling frail older adults with diabetes: Using phenomenological methods
- 재가장기요양서비스 이용 노인의 삶의 의미 영향요인: 서술적 단면 조사 연구
- 요양병원 간호사의 낙상예방행위 영향요인: 서술적 조사연구
최근 이용한 논문
교보eBook 첫 방문을 환영 합니다!
신규가입 혜택 지급이 완료 되었습니다.
바로 사용 가능한 교보e캐시 1,000원 (유효기간 7일)
지금 바로 교보eBook의 다양한 콘텐츠를 이용해 보세요!