Furosemide 이뇨중의 내당능 및 Insulin 반응에 미치는 K 또는 Ca 보충투여의 영향

• 영문명: Effects of K or Ca Supplement on Glucose Tolerance and Insulin Response in Subjects with Furosemide Diuresis
• 발행기관: 대한생리학회
• 저자명: 성호경(Sung, Ho-Kyung) 고주환(Koh, Joo-Hwan) 유용운(Ryu, Yong-Woon)
• 간행물 정보: 『대한생리학회지』제10권 제2호, 29~38쪽, 전체 10쪽
• 주제분류: 의약학 > 의학일반
• 파일형태: PDF
• 발행일자: 1976.12.31

영문 초록

Effect of furosemide administration on glucose tolerance, insulin-and HGH response following parenteral glucose loading was studied in healthy subjects. Effects of potassium or calcium on the furosemide induced changes were also observed in the same subjects. Furosemide administration resulted in a considerable reduction in the magnitude and duration of insulin response although no obvious changes were observed in glucose disappearance from the circulation. Oral potassium or calcium supplement to the furosemide treated subjects showed a reversion toward normal of the insulin response. The author suggested that a decreased endogenous insulin production resulting from the potassium and/or calcium depletion is responsible for the changes observed. In those subjects who receive parenteral nutrition if administration of furosemide is essential, it should be supplemented by potassium and/or calcium.