산사육복합방(山査肉複合方)이 생쥐의 비만억제에 미치는 영향

• 영문명: The Inhibitory Effects of Sansayukbokhap-bang,SSYBHB on the Obese-Mouse Induced High Fat Diet
• 발행기관: 한방비만학회
• 저자명: 김형준(Hyong Jun Kim) 홍서영(Seo Young Hong) 허동석(Dong Seok Heo) 윤일지(Il Ji Yoon) 오민석(Min Seok Oh)
• 간행물 정보: 『대한한방비만학회지』제8권 1호, 33~49쪽, 전체 17쪽
• 주제분류: 의약학 > 한의학
• 파일형태: PDF
• 발행일자: 2008.06.30

영문 초록

In order to investigate the effects of Sansayukbokhap-bang (SSYBHB) on the hematological and histological changes. Methods C57BL/6 mice were fed with high fat diet. C57BL/6 mice were divided into four groups and fed for 15weeks. Results 1. The body weight of SSYBHB intake mice was significantly lower than high fat diet group. 2. The final increase of body weight was decreased significantly. 3. The levels of ALT, AST, total cholesterol, LDL-Cholesterol, triglyceride, Leptin were decreased significantly. 4. The levels of creatinine were decreased but did not show significance. 5. The level of HDL-cholesterol and the expression of β3AR mRNA gene in 3T3-L1 Adipocytes were increased significantly. 6. Adipocytes`` size was decreased significantly. 7. The expression of β3AR mRNA gene, Leptin mRNA gene and serotinin mRNA gene in Adipocytes tissue was decreased significantly. Conclusion Based on these results, it is proved that SSYBHB is effective on the therapy of obesity by referring to obese-gene and obese inhibitory. So, it is espected that the clinical application of SSYBHB can help the treatment of obesity.

목차

Ⅰ. 緖 論

Ⅱ. 實驗材料 및 方法

Ⅲ. 結 果

Ⅳ. 考 察

Ⅴ. 結 論

Ⅵ. 參考文獻

키워드

Sansayukbokhap-bang obesity C57BL 6mice body weight