비만환자에 대한 방풍통성산(防風通聖散)의 무작위배정, 이중맹검, 위약-대조군 임상시험

• 영문명: Randomized, Double Blind, Placebo-Controlled Study of Bofu-tsusho-san on Obese Patients
• 발행기관: 한방비만학회
• 저자명: 이지은(Ji Eun Lee) 송윤경(Yun Kyung Song) 임형호(Hyung Ho Lim)
• 간행물 정보: 『대한한방비만학회지』제10권 2호, 1~16쪽, 전체 16쪽
• 주제분류: 의약학 > 한의학
• 파일형태: PDF
• 발행일자: 2010.12.31

영문 초록

The clinical trial was designed to investigate the safety and effects of Bofu-tsusho-san extracts on the change of the weight, body compositions, serum in obese patients. Methods This study was a 4-weeks, double blind, comparative clinical trial. Eligible subjects had a body mass index(BMI) greater than 25 kg/m² and waist circumference(WC) longer than 85 cm in woman or 90 cm in man. Among 38 subjects, 36 subjects were randomized either to Bofu-tsusho-san or placebo. After 4 weeks of treatment, we measured anthropometric factors(weight, height, WC, BMI etc.), abdominal fat area by CT scanning, serum lipid(total cholesterol(TC), triglyceride(TG), HDL cholesterol, LDL cholesterol), blood level of variety(glucose, adiponectine, leptin, C-reactive protein(CRP) etc.), blood pressure(BP). Adverse events also evaluated. Results BMI, BP, TG, CRP were reduced and weight, WC, score of KOQOL(Korean version of obesity-related QOL scale), SRI(Stress response inventory) were significant changed in Bofu-tsusho-san. But there were no considerable difference between Bofu-tsusho-san and placebo. there were no serious adverse events in either group. Conclusion There were limitations in this study that it conducted within a short period of 4 weeks. but its weight and WC loss effect was significant and it had few adverse events.

목차

Ⅰ. 서 론

Ⅱ. 연구대상 및 방법

Ⅲ. 연구 결과

Ⅳ. 고 찰

Ⅴ. 결 론

Ⅵ. 감사의 글

Ⅶ. 참고문헌

키워드

Obesity Bofu-tsusho-san Efficacy Safety