오약순기산 발효물의 급성 독성에 관한 연구

• 영문명: Study on Acute Toxicity of Fermented Ohyaksungi-san, Wuyaoshunqi-san Extracts
• 발행기관: 한방비만학회
• 저자명: 이지혜(Ji Hye Lee) 곽동훈(Dong Hoon Kwak) 김태수(Tae Soo Kim) 마진열(Jin Yeul Ma)
• 간행물 정보: 『대한한방비만학회지』제11권 2호, 25~32쪽, 전체 8쪽
• 주제분류: 의약학 > 한의학
• 파일형태: PDF
• 발행일자: 2011.12.31

영문 초록

The purpose of this study was to investigate the acute toxicity with oral administration in ICR mice of Ohyaksungi-san fermented with Lactobacillus sp. Methods In single oral administered toxic test, four groups were administrated different dosages(0, 1250, 2500, 5000 ㎎/㎏) of fermented Ohyaksungi-san. After single oral administration, we observed number of death, clinical signs, body weight changes, hematological values and autopsy. Results Compared with the control group, we could not find any toxic signs in the mortalities, clinical signs, body weight changes, necropsy findings and hematological values in all treated groups (1250, 2500 and 5000 ㎎/㎏). Conclusions These results indicate that the LD50 value of fermented Ohyaksungi-san extract might be over 5000 ㎎/㎏ and it have no side toxic effect to ICR mice

목차

Ⅰ. 서 론

Ⅱ. 재료 및 방법

Ⅲ. 결 과

Ⅳ. 고 찰

Ⅴ. 결 론

Ⅵ. 감사의 글

Ⅶ. 참고문헌

키워드

Ohyaksungi-san Fermentation Safety LD50