모유 섭취를 통한 영아의 과불화화합물 노출량에 관한 문헌고찰(2008~2024)

• 영문명: A Review on Exposure to Per- and Polyfluoroalkyl Substances (PFAS) via Breastfeeding in Infants (2008~2024)
• 발행기관: 한국환경보건학회
• 저자명: 문나래(Nalae Moon) 김주희(Ju Hee Kim)
• 간행물 정보: 『한국환경보건학회지』제51권 제1호, 1~10쪽, 전체 10쪽
• 주제분류: 공학 > 환경공학
• 파일형태: PDF
• 발행일자: 2025.02.28

국문 초록

Background: Perfluoroalkyl substances (PFAS) that accumulate in mothers through daily exposure can be directly transferred to newborns via breastfeeding, potentially resulting in health issues. However, existing studies on PFAS concentrations and exposure through breast milk exhibit significant heterogeneity, hindering systematic comparisons. Objectives: This study aims to compare the findings of previous studies on PFAS concentrations in breast milk and exposure and identify limitations to suggest directions for future research. Methods: Using a scoping review methodology, relevant studies were identified from Google Scholar and PubMed that analyzed PFOA, PFOS, PFHxS, and PFNA concentrations in human breast milk. The analyzed variables included target PFAS substances, number of breast milk samples, study countries, limits of detection (LOD) or quantification (LOQ), detection rates, timing of sample collection, analytical methods, and infant PFAS exposure levels. Results: PFAS concentrations in breast milk (PFOA, PFOS, PFHxS, PFNA) varied depending on sample collection timing, geographical region, milk maturity, maternal characteristics, analytical methods, and detection limits, highlighting significant heterogeneity among studies. Oral exposure to PFAS through breastfeeding in recent studies exceeded the tolerable weekly intake (TWI), indicating potential risks to infants. Conclusions: This study underscores the need for additional research to accurately assess PFAS contamination and exposure in breast milk and facilitate quantitative comparisons between studies. Furthermore, it highlights the importance of policy interventions to reduce maternal exposure to PFAS, ensuring better health outcomes for infants and mothers alike.

목차

I. 서 론

II. 연구방법

III. 연구 결과

IV. 고 찰

V. 결 론

감사의 글

Conflict of Interest

References

키워드

Breast milk PFAS exposure EDI TWI