Intrathyroidal Parathyroid Hyperplasia Misdiagnosed as Hurthle Cell Neoplasm

• 영문명: Intrathyroidal Parathyroid Hyperplasia Misdiagnosed as Hurthle Cell Neoplasm
• 발행기관: 대한내분비외과학회
• 저자명: Jin Kyong Kim Gi Jeong Kim Jongtae Cha Sang-Wook Kang Jong Ju Jeong Kee-Hyun Nam Woong Youn Chung
• 간행물 정보: 『The Koreran journal of Endocrine Surgery』24권1호, 19~24쪽, 전체 6쪽
• 주제분류: 의약학 > 면역학
• 파일형태: PDF
• 발행일자: 2024.03.30

영문 초록

This case report details the medical history of a 60-year-old male with end-stage renal disease undergoing hemodialysis. The patient was referred for an assessment of thyroid nodules. Ultrasound revealed probably benign nodules of 2.6 cm and 1.4 cm in the right and left thyroid poles, respectively. The right thyroid nodule was confirmed as a Hurthle cell neoplasm through a core needle biopsy. Laboratory tests indicated elevated serum parathyroid hormone (PTH) and calcium levels, suggesting secondary hyperparathyroidism. Subsequent evaluations, including a parathyroid scan and single photon emission computed tomography-computed tomography, identified probable parathyroid adenomas displaying increased radiotracer uptake. Moreover, delayed images revealed heightened uptake in two intrathyroidal nodules detected during recent ultrasonography. Intraoperative PTH measurements exhibited a significant 66.5% decline following the resection of the right thyroid. While frozen sections of the right thyroid indicated Hurthle cell proliferative lesions, the final histopathological examination unveiled nodular parathyroid hyperplasia. This case underscores the challenges in distinguishing between thyroid and parathyroid pathologies and underscores the importance of comprehensive assessments in managing such cases.

목차

INTRODUCTION

CASE REPORT

DISCUSSION

ACKNOWLEDGMENTS

REFERENCES

키워드

Parathyroid adenoma Primary hyperparathyroidism Hurthle cell tumor Thyroid nodule