학술논문
Metabolic Syndrome as a Prognostic Factor in Papillary Thyroid Cancer Patients
이용수 5
- 영문명
- Metabolic Syndrome as a Prognostic Factor in Papillary Thyroid Cancer Patients
- 발행기관
- 대한내분비외과학회
- 저자명
- Hyeong Eun Jeong Ha Rim Ahn Sang Yull Kang Hyun Jo Youn Sung Hoo Jung
- 간행물 정보
- 『The Koreran journal of Endocrine Surgery』23권4호, 113~122쪽, 전체 10쪽
- 주제분류
- 의약학 > 면역학
- 파일형태
- 발행일자
- 2023.12.31
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국문 초록
영문 초록
Purpose: Metabolic syndrome (MetS) is considered a risk factor and poor prognostic factor for several cancers, and increases the risk of thyroid cancer and aggressiveness of papillary thyroid cancer (PTC). Here, we investigated the association between a poor prognosis in patients with PTC, and MetS.
Methods: Patients diagnosed with PTC who underwent thyroidectomy between January 2013 and December 2015 at our institution were included (n=789). We divided patients into two groups according to the presence of MetS—defined as three or more of the following criteria: central obesity, hypertension, insulin resistance, low high-density lipoprotein cholesterol, and high triglycerides—identified by retrospective medical record review. We analyzed the clinicopathologic factors between the two groups, univariate and multivariate analyses were performed, and survival outcomes were analyzed by propensity score matching.
Results: The mean patient age and median follow-up period were 47.0±11.2 years and 6.14 years, respectively; 119 patients (15.1%) were diagnosed with MetS. Significant differences between groups were identified regarding sex, age, operation extent, central neck dissection, lateral neck dissection, extrathyroidal extension (ETE), lateral lymph node metastasis, T stage, N stage, and radioactive iodine therapy. Old age, ETE, and MetS were identified as prognostic factors of recurrence-free survival (RFS) in the multivariate analysis. The 5-year RFS rates were 94.9% and 99.1% in the non-MetS and MetS groups, respectively, which was statistically significant (P=0.021).
Conclusion: MetS is a prognostic factor for RFS among patients with PTC in our hospital.
목차
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
CONCLUSION
REFERENCES
해당간행물 수록 논문
- Incidental Finding of a Small Schwannoma Originating From the Recurrent Laryngeal Nerve During Thyroidectomy: A Case Report
- Metabolic Syndrome as a Prognostic Factor in Papillary Thyroid Cancer Patients
- Malignant Struma Ovarii With Graves’ Disease and Papillary Thyroid Carcinoma: A Case Report
- Comparing Outcomes in Video-Assisted and Open Parathyroidectomy for Patients With Primary Hyperparathyroidism: A Systematic Review and Meta-Analysis
- Supernumerary Mediastinal Parathyroid Carcinoma Resulting in Recurrent Primary Hyperparathyroidism and Hypercalcemic Crisis: A Case Report
- Tract Site Seeding of Papillary Thyroid Cancer After Transoral Endoscopic Thyroidectomy: A Case Report
- Protruding Huge Thyroid Mass Concurrent Hemorrhage and Skin Necrosis: A Case Report
참고문헌
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