갑상선 MALT 림프종으로부터 전환된 미만성 거대 B세포 림프종 1예

• 영문명: A Case of Diffuse Large B-cell Lymphoma Transformed from Primary Thyroid MALT Lymphoma
• 발행기관: 대한두경부종양학회
• 저자명: 조영록 조윤진 표주연 이혜란
• 간행물 정보: 『대한두경부종양학회지』제39권 제2호, 13~17쪽, 전체 5쪽
• 주제분류: 의약학 > 종양학
• 파일형태: PDF
• 발행일자: 2023.11.30

국문 초록

Diffuse large B cell lymphoma (DLBCL) is main subtype of primary thyroid lymphoma and can be histologically transformed from a low-grade B-cell lymphoma. The characteristics and treatment guidelines of these particular DLBCL have not been fully established. The mainstay of treatment of primary thyroid DLBCL is multimodality treatment with chemotherapy and radiotherapy. Meanwhile, surgery can be considered only for diagnosis or alleviation of airway compressive symptoms. A 57-year-old female visited our outpatient clinic for recently enlarged long-held anterior neck mass. A thyroid mass compressing the airway and esophagus was identified on imaging, which was diagnosed as MALT lymphoma by excisional biopsy. After staging, the patient underwent total thyroidectomy with regional lymph node dissection for treatment of stage IIE MALT lymphoma and relieving airway compromise symptoms. The final diagnosis was DLBCL transformed from MALT Lymphoma, and chemotherapy was additionally performed. We report this rare experience with a review of literature.

키워드

Primary thyroid lymphoma MALT lymphoma Diffuse large B-cell lymphoma Histologic transformation