단일기관 증례 기반의 개두술 후 수술 부위 감염의 발생률과 미생 물학적 관점의 고찰

• 영문명: Incidence and microbiology of surgical site infection in cranial neurosurgery in recent era: Single institutional consecutive series and review of literature
• 발행기관: 대한두개저학회
• 저자명: 권유현 노해원 조현준 윤원기 김종현 권택현 변준호
• 간행물 정보: 『대한두개저학회지』제18권 제2호, 92~104쪽, 전체 13쪽
• 주제분류: 의약학 > 일반외과학
• 파일형태: PDF
• 발행일자: 2023.10.31

영문 초록

Background: Surgical site infection (SSI) is the most common healthcare-associated infection. Neurosurgical SSI results in severe morbidity and high mortality. This study aims to review our insti-tutional series of SSIs after cranial surgery, identify risk factors and pathogens, and enhance surgical outcomes through literature review. Materials and Methods: A retrospective, single-institutional study was conducted, craniotomy and craniectomy from January 2021 to December 2022 were included. Risk factors of all cases and pathogens, treatments, and outcomes of infected cases were collected and statistically analyzed. Results: Out of total 391 cases, 8 cases (2.0%) from six different type of surgeries, and diseases were diagnosed SSI. Four different pathogens were isolated, but pathogen was not identified in 4 cases (50.0%). The isolated pathogens included methicillin-sensitive Staphylococcus aureus , methicillin-resistant S. aureus , Bacillus cereus , and multi-drug resistant Acinetobacter baumannii . Among the eight cases, there were 2 cases (25.0%) of superficial SSI, 4 cases (50.0%) of deep SSI, and 2 cases (25.0%) of organ/space SSI. Two cases (25.0%) were managed with antibiotics alone, abscess was drained in 2 cases (25.0%), and revisional surgery was conducted in 4 cases (50.0%). Conclusions: Out of the 8 cases of SSI, a half of the isolated strains were multi-drug resistant. All infections were successfully treated without complications. However, guidelines for treatment of neu-rosurgical site infection were insufficient. The increasing prevalence of multi-drug resistant bacterial infection underscores the necessity of treatment consensus for the future.

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INTRODUCTION

METHODS

RESULTS

DISCUSSION

CONFLICT OF INTEREST

ORCID

REFERENCES

키워드

Surgical site infection Craniotomy Bacterial infection Drug resistance