임상적 비기능성 뇌하수체 종양의 미세현미경적 가성피막의 제거

• 영문명: Microsurgical Pseudocapsule Resection of Clinically Nonfunctioning Pituitary Tumors
• 발행기관: 대한두개저학회
• 저자명: 김병우(Byeong Woo Kim) 심유식(Yu Shik Shim) 장종희(Jong Hee Chang) 안정용(Jung Yong Ahn) 김선호(Sun Ho Kim)
• 간행물 정보: 『대한두개저학회지』제3권 제1호, 21~25쪽, 전체 5쪽
• 주제분류: 의약학 > 일반외과학
• 파일형태: PDF
• 발행일자: 2008.06.30

영문 초록

Objective : The aim of this study was to investigate the precise histological characteristics of the boundary, using surgical specimens from patients who underwent intensive resection of “microsurgical pseudocapsule”of clinically non-functioning pituitary tumors (CNPTs). Furthermore, we compared the remission rate of CNPTs between subjects with (Group 1) and without (Group 2) intensive resection of microsurgical pseudocapsule in order to correlate the histological complete resection and endocrinological remission. Patients and Methods : Between January 2000 and December 2007, 113 patients underwent intensive microsurgical dissection during the transsphenoidal surgery in one hospital (Group 1). In the other hand, 24 patients underwent conventional subcapsular resection without intentionally removing the microsurgical pseudocapsule in another hospital (Group 2). Results : The overall surgical remission rate in Group 1 with intensive resection of microsurgical pseudocapsule were statistically higher than the rates in Group 2 (without intensive resection of microsurgical pseudocapsule) (p=0.032). However, there were no statistical differences in postoperative hormonal function change between Group 1 and 2. Conclusions : Our results indicate that aggressive resection of psuedocapsules increases the cure rate without aggravating pituitary function.

목차

Introduction

Patients and Methods

Results

Discussion

키워드

Pituitary tumors Pseudocapsule Transsphenoidal surgery Remission